ArticleThe British journal of radiology2017
Factors influencing brown fat activation in FDG PET/CT: a retrospective analysis of 15,000+ cases.
Article in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Nutrition/Diet on Brown Adipose Tissue in Humans: A Systematic Review and Meta-Analysis.Nutrients · 2020Pooled it
- Prevention of activated brown adipose tissue onScientific reports · 2023Trial
- Determinants of activity of brown adipose tissue in lymphoma patients.Scientific reports · 2020Trial
- ATP synthase is a promising target for identifying activated and non-activated adipose tissues.Nature communications · 2026Article
- Fatty acids promote uncoupled respiration via ATP/ADP carriers in white adipocytes.Nature metabolism · 2026Article
- Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways.International journal of molecular sciences · 2026Review
- Does the addition of fentanyl premedication impact brown fat uptake in children undergoing a warming protocol for FDG PET?Pediatric radiology · 2025Article
- Effect of β3-adrenergic receptor agonists on [EJNMMI research · 2025Article
- Brown adipose tissue activity on PET/CT and the course of Hodgkin lymphoma.Journal of cancer research and clinical oncology · 2025Article
- Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging.Nature metabolism · 2024Article
- Characterising polymyalgia rheumatica on whole-bodyRheumatology advances in practice · 2024Review
- Memories and mimics: unveiling the potential of FDG-PET in guiding therapeutic approaches for neurodegenerative cognitive disorders.Frontiers in neurology · 2024Review
- Mirabegron displays anticancer effects by globally browning adipose tissues.Nature communications · 2023Article
- Off the Beaten Path in Oncology: Active Brown Adipose Tissue by Virtue of Molecular Imaging.Current issues in molecular biology · 2023Article
- 2-deoxy-2-[Molecular imaging and biology · 2023Article
- Intense Brown Fat Uptake at FDG PET/CT Induced by Mirabegron.Radiology. Imaging cancer · 2023Article
- Brown Adipose Tissue-A Translational Perspective.Endocrine reviews · 2023Review
- Brown adipose tissue is not associated with cachexia or increased mortality in a retrospective study of patients with cancer.American journal of physiology. Endocrinology and metabolism · 2023Article
- Treatment Resulting Changes in Volumes of High-International journal of molecular sciences · 2023Article
- The evolving view of thermogenic fat and its implications in cancer and metabolic diseases.Signal transduction and targeted therapy · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBrown fat can exhibit high uptake of fluorine-18 fludeoxyglucose (
methodsA retrospective study of
resultsThe total reported BAT activation was 3.6%. BAT activation was reported significantly more often in patients who were female (p < 0.0001), younger (p < 0.0001), with lower body mass index (p < 0.0001), with lower blood glucose levels (p = 0.01), indicated for breast cancer (p = 0.004), not administered chemotherapy recently before the scan (p < 0.0001) and shown to have BAT activation in a previous scan (p < 0.0001). BAT activation was also reported significantly more for lower outdoor temperatures (p < 0.0001) and for late morning scans than for afternoon (p = 0.005) and early morning (p = 0.001) scans.
conclusionThis retrospective study of 15,109 scans highlights multiple factors contributing to BAT activation on
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.