ArticleInternational journal of environmental research and public health2017
Environmental Factors Associated with Type 1 Diabetes Development: A Case Control Study in Egypt.
Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Vitamin supplementation and its effect on incident type 1 diabetes mellitus and islet autoimmunity: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Maternal infection during pregnancy and type 1 diabetes mellitus in offspring: a systematic review and meta-analysis.Epidemiology and infection · 2018Pooled it
- Gestational diabetes and parental type 2 diabetes as risk indicators for type 1 diabetes in offspring: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Detecting Disordered Eating Behaviors in Greek Youth with Type 1 Diabetes Mellitus by Using the Diabetes Eating Problem Survey-Revised (DEPS-R): Associations with Insulin Restriction, Glycemic Control, and Anthropometric Parameters.Children (Basel, Switzerland) · 2025Article
- The potential Association of Bisphenol A exposure and type 1 diabetes mellitus among Dakahlia Governorate's children sample, Egypt.Toxicology research · 2024Article
- Breastfeeding, nutrition and type 1 diabetes: a case-control study in Izmir, Turkey.International breastfeeding journal · 2022Article
- Environmental Factors and the Risk of Developing Type 1 Diabetes-Old Disease and New Data.Biology · 2022Review
- Stress Hyperglycemia in Children and Adolescents as a Prognostic Indicator for the Development of Type 1 Diabetes Mellitus.Frontiers in pediatrics · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uncertainty still exists regarding the role of some environmental risk in the development of type 1 diabetes mellitus (T1DM) both globally and in Egypt. The objective here was to explore the potential environmental risk factors associated with the development of T1DM among children in Egypt. A case-controlled study of 204 T1DM children and an equal number of age and sex-matched controls was conducted in Assiut, Egypt. Data regarding the parental, gestational, neonatal, and childhood possible risk factors for T1DM were evaluated. The final sex adjusted multivariable logistic regression model revealed that the risk for T1DM was significantly higher among rural residents (aOR = 2.03, 95% CI: 1.30-4.25), those with parental history of T1DM (aOR = 9.03, 95% CI: 1.02-83.32), birth through cesarean section (aOR = 2.13, 95% CI: 1.09-5.03), and having history of early introduction of cow milk in the first year of life (aOR = 19.49, 95% CI: 8.73-45.53). On the other hand, a protective effect was observed between at least six months' breastfeeding, vitamin D supplementation in the first year of life, high physical activity, and the development of T1DM. Educational programs should be adopted to improve awareness and knowledge of the parents to avoid the increased risk factors and encourage protective practices.
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