ArticleAIDS (London, England)2017
Sexual partnership age pairings and risk of HIV acquisition in rural South Africa.
Article in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: a systematic review and meta-analysis.The Lancet. Global health · 2019Pooled it
- Partner age differences and associated sexual risk behaviours among adolescent girls and young women in a cash transfer programme for schooling in Malawi.BMC public health · 2018Trial
- The age and sex dynamics of heterosexual HIV transmission in Zambia: an HPTN 071 (PopART) phylogenetic and modelling study.medRxiv : the preprint server for health sciences · 2026Article
- Evaluating the biomedical and behavioral drivers of HIV incidence decline in adolescent girls and young women in Uganda: A mathematical modeling study.PLoS medicine · 2026Article
- Factors associated with multiple sexual partnerships among men in South Africa.BMC public health · 2025Article
- Article
- Prevalence of detectable viral load and its associated factors among adult patients receiving ART in Choma District, Zambia.PloS one · 2025Article
- Age-disparate and intergenerational sex partnerships and HIV: the role of gender norms among adolescent girls and young women in Malawi.BMC public health · 2024Article
- Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda.Nature microbiology · 2024Article
- Developing HIV risk prediction tools in four African settings.Tropical medicine & international health : TM & IH · 2023Article
- The dynamics of sexual risk amongst South African youth in age-disparate relationships.Frontiers in reproductive health · 2023Article
- The impact of prevention-effective PrEP use on HIV incidence: a mathematical modelling study.Journal of the International AIDS Society · 2022Article
- Risks and benefits of oral HIV pre-exposure prophylaxis for people with chronic hepatitis B.The lancet. HIV · 2022Review
- Article
- The HIV Epidemic in South Africa: Key Findings from 2017 National Population-Based Survey.International journal of environmental research and public health · 2022Article
- Determining HIV risk for Adolescent Girls and Young Women (AGYW) in relationships with "Blessers" and age-disparate partners: a cross-sectional survey in four districts in South Africa.BMC public health · 2022Article
- The geography and inter-community configuration of new sexual partnership formation in a rural South African population over fourteen years (2003-2016).PLOS global public health · 2022Article
- Prediction of HIV status based on socio-behavioural characteristics in East and Southern Africa.PloS one · 2022Article
- Prevalence and Risk Factors for HIV Infection Among Heterosexual Men Recruited from Socializing Venues in Rural KwaZulu-Natal, South Africa.AIDS and behavior · 2021Article
- Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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6 authors.
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Abstract
objectiveTo quantify the contribution of specific sexual partner age groups to the risk of HIV acquisition in men and women in a hyperendemic region of South Africa.
designWe conducted a population-based cohort study among women (15-49 years of age) and men (15-55 years of age) between 2004 and 2015 in KwaZulu-Natal, South Africa.
methodsGeneralized additive models were used to estimate smoothed HIV incidence rates across partnership age pairings in men and women. Cox proportional hazards regression was used to estimate the relative risk of HIV acquisition by partner age group.
resultsA total of 882 HIV seroconversions were observed in 15 935 person-years for women, incidence rate = 5.5 per 100 person-years [95% confidence interval (CI), 5.2-5.9] and 270 HIV seroconversions were observed in 9372 person-years for men, incidence rate = 2.9 per 100 person-years (95% CI, 2.6-3.2). HIV incidence was highest among 15-24-year-old women reporting partnerships with 30-34-year-old men, incidence rate = 9.7 per 100 person-years (95% CI, 7.2-13.1). Risk of HIV acquisition in women was associated with male partners aged 25-29 years (adjusted hazard ratio; aHR = 1.44, 95% CI, 1.02-2.04) and 30-34 years (aHR = 1.50, 95% CI, 1.08-2.09) relative to male partners aged 35 and above. Risk of HIV acquisition in men was associated with 25-29-year-old (aHR = 1.72, 95% CI, 1.02-2.90) and 30-34-year-old women (aHR = 2.12, 95% CI, 1.03-4.39) compared to partnerships with women aged 15-19 years.
conclusionAge of sexual partner is a major risk factor for HIV acquisition in both men and women, independent of one's own age. Partner age pairings play a critical role in driving the cycle of HIV transmission.
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