ArticleAIDS (London, England)2017
Pregnancy incidence and outcomes in women with perinatal HIV infection.
Article in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Incidence and predictors of pregnancy among reproductive-age women in an ART clinic of public health facilities in Arsi zone, southeastern ethiopia: a five-year retrospective cohort study.BMC women's health · 2025Article
- Pregnancy Outcomes and All-Cause Mortality After Pregnancy Among US-Born Women With Perinatally Acquired HIV.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Routine Vaccination During Pregnancy Among People Living With HIV in the United States.JAMA network open · 2024Article
- Adults with Perinatally Acquired HIV; Emerging Clinical Outcomes and Data Gaps.Tropical medicine and infectious disease · 2024Review
- Sexual and reproductive health needs of young women living with perinatally acquired HIV.International journal of STD & AIDS · 2023Article
- Pregnancy in women living with perinatally acquired HIV: Perinatal outcomes and drug resistance profile.Clinics (Sao Paulo, Brazil) · 2023Article
- Effect of predictors on incidence rate of pregnancy among reproductive age women on antiretroviral therapy at public hospitals of Jigjiga and Harar Towns, Eastern Ethiopia: a retrospective cohort study.BMC women's health · 2022Article
- Trends in antiretroviral use in pregnancy in the UK and Ireland, 2008-2018.HIV medicine · 2022Article
- Second-generation mother-to-child HIV transmission in South Africa is characterized by poor outcomes.AIDS (London, England) · 2021Observational
- Adverse Birth Outcomes in Botswana Among Women With Vertically or Horizontally Acquired Human Immunodeficiency Virus.Journal of the Pediatric Infectious Diseases Society · 2021Article
- The next generation: Pregnancy in adolescents and women living with perinatally acquired HIV in South Africa.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2021Article
- Repeat Pregnancies Among US Women Living With HIV in the SMARTT Study: Temporal Changes in HIV Disease Status and Predictors of Preterm Birth.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Behavioral Health and Adult Milestones in Young Adults With Perinatal HIV Infection or Exposure.Pediatrics · 2018Article
- Simulation Modeling and Metamodeling to Inform National and International HIV Policies for Children and Adolescents.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Pregnancies in perinatally HIV-infected women: antiretroviral treatment strategies, obstetric and virologic outcomes.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo estimate the incidence of first pregnancy in women living with perinatally acquired HIV (PHIV) in the United Kingdom and to compare pregnancy management and outcomes with age-matched women with behaviourally acquired HIV (BHIV).
designThe National Study of HIV in Pregnancy and Childhood is a comprehensive, population-based surveillance study that collects demographic and clinical data on all pregnant women living with HIV, their children, and all HIV-infected children in the United Kingdom and Ireland.
methodsThe incident rate ratio of first pregnancy was calculated for all women of reproductive age who had been reported to the National Study of HIV in Pregnancy and Childhood as vertically infected children. These women and their pregnancies were compared to age-matched pregnant women with BHIV.
resultsOf the 630 women with PHIV reported in the United Kingdom as children, 7% (45) went on to have at least one pregnancy, with 70 pregnancies reported. The incident rate ratio of first pregnancy was 13/1000 woman-years. The BHIV comparison group comprised 118 women (184 pregnancies). Women with PHIV were more likely to be on combined antiretroviral therapy at conception and have a lower baseline CD4 cell count (P < 0.01 for both). In adjusted analysis, PHIV and a low baseline CD4 cell count were risk factors for detectable viral load near delivery; older age at conception and being on combined antiretroviral therapy at conception reduced this risk.
conclusionWomen with PHIV in the United Kingdom have a low pregnancy incidence, but those who become pregnant are at risk of detectable viral load near delivery, reflecting their often complex clinical history, adherence, and drug resistance issues.
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