Evidence map›Paper›PMID 28590251›Full record

ReviewClinical microbiology reviews2016

A Primer on Infectious Disease Bacterial Genomics.

Tarah Lynch, Aaron Petkau, Natalie Knox, Morag Graham, Gary Van Domselaar

Abstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Molecular Characterization of Multidrug-ResistantFrontiers in microbiology · 2021
    Article
  5. Article
  6. Molecular Epidemiology of Carbapenemases inAntibiotics (Basel, Switzerland) · 2020
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. New Insights intoFrontiers in microbiology · 2018
    Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tarah LynchDivision of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada tarah.lynch@ahs.ca.
Aaron PetkauNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Natalie KnoxNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Morag GrahamNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Gary Van DomselaarNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of large-scale genomics projects is increasing due to the availability of affordable high-throughput sequencing (HTS) technologies. The use of HTS for bacterial infectious disease research is attractive because one whole-genome sequencing (WGS) run can replace multiple assays for bacterial typing, molecular epidemiology investigations, and more in-depth pathogenomic studies. The computational resources and bioinformatics expertise required to accommodate and analyze the large amounts of data pose new challenges for researchers embarking on genomics projects for the first time. Here, we present a comprehensive overview of a bacterial genomics projects from beginning to end, with a particular focus on the planning and computational requirements for HTS data, and provide a general understanding of the analytical concepts to develop a workflow that will meet the objectives and goals of HTS projects.

Indexed as

GenomicsCommunicable DiseasesGenome, BacterialHigh-Throughput Nucleotide SequencingHumans

Identifiers

PMID28590251
PMCPMC5010755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.