ArticleThe Journal of general virology2017
A porcine enterovirus G associated with enteric disease contains a novel papain-like cysteine protease.
Article in The Journal of general virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Virus Metagenomics in Farm Animals: A Systematic Review.Viruses · 2020Pooled it
- Development and evaluation of a single-tube RT-ERA-CRISPR/Cas12a assay for simultaneous detection of enterovirus G and recombinant strains with papain-like cysteine protease gene insertion.Veterinary research communications · 2026Article
- Article
- Fecal metatranscriptomics and virus isolation reveal picornavirus diversity and evolution in Japanese wild boars and pigs.Scientific reports · 2026Article
- First detection of a recombinant enterovirus G carrying a torovirus papain-like cysteine protease gene from India.Virus genes · 2026Article
- Phylogenetic analysis of enteroviruses from non-human primates suggests two new species within the genusVirus evolution · 2026Article
- Construction of enterovirus G expressing reporter genes for antiviral drug screening assays.BMC veterinary research · 2025Article
- Isolation and characterization of an enterovirus G strain causing diarrhea and gut microbiota dysbiosis in piglets.Frontiers in cellular and infection microbiology · 2025Article
- Article
- First isolation, identification, and pathogenicity evaluation of an EV-G6 strain in China.Frontiers in veterinary science · 2024Article
- Systematic Surveillance of an Emerging Picornavirus among Cattle and Sheep in China.Microbiology spectrum · 2023Article
- DL-TODA: A Deep Learning Tool for Omics Data Analysis.Biomolecules · 2023Article
- Novel recombinant porcine enterovirus G viruses lacking structural proteins are maintained in pig farms in Japan.The Journal of veterinary medical science · 2023Article
- Distribution and genetic diversity of Enterovirus G (EV-G) on pig farms in Thailand.BMC veterinary research · 2021Article
- Article
- Recent Progress in Torovirus Molecular Biology.Viruses · 2021Review
- Characterization and Identification of a Novel Torovirus Associated With Recombinant Bovine Torovirus From Tibetan Antelope in Qinghai-Tibet Plateau of China.Frontiers in microbiology · 2021Article
- Isolation, Identification, and Evaluation of the Pathogenicity of a Porcine Enterovirus G Isolated From China.Frontiers in veterinary science · 2021Article
- Characterization of Self-Processing Activities and Substrate Specificities of Porcine Torovirus 3C-Like Protease.Journal of virology · 2020Article
- Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and Limitations.Pharmaceuticals (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identification of unknown pathogens in pigs displaying enteric illness is difficult due to the large diversity of bacterial and viral species found within faecal samples. Current methods often require bacterial or viral isolation, or testing only a limited number of known species using quantitative PCR analysis. Herein, faeces from two 25-day-old piglets with diarrhoea from Texas, USA, were analysed by metagenomic next-generation sequencing to rapidly identify possible pathogens. Our analysis included a bioinformatics pipeline of rapid short-read classification and de novo genome assembly which resulted in the identification of a porcine enterovirus G (EV-G), a complete genome with substantial nucleotide differences (>30 %) among current sequences, and a novel non-structural protein similar in sequence to the Torovirus papain-like cysteine protease (PLpro). This discovery led to the identification and circulation of an EV-G with a novel PLpro in the USA that has not been previously reported.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.