Evidence map›Paper›PMID 28589946›Full record

ArticleMucosal immunology2018

Elevated prostaglandin E

G J Martínez-Colón, Q M Taylor, C A Wilke, A B Podsiad, B B Moore

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The Link between Prostanoids and Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Prostaglandin EPharmacology & therapeutics · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

G J Martínez-ColónImmunology Graduate Program, University of Michigan, Ann Arbor, Michigan, USA.
Q M TaylorLiterature, Sciences and the Arts, Microbiology, University of Michigan, Ann Arbor, Michigan, USA.
C A WilkePulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
A B PodsiadPulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
B B MoorePulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan–Ann Arbor · US

Funding

RESEARCH TRAINING IN EXPERIMENTAL IMMUNOPATHOLOGYT32AI007413 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bethany B. Moore · 1993 to 2026
$9.8M
University of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1M
miR-29b and autophagy regulate alveolar macrophage function post-BMTR01AI117229 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2015 to 2019
$2.2M
Post Viral Bacterial Pneumonia: Role of MicroRNA and AutophagyR01HL119682 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2014 to 2017
$1.5M
HSCT-induced alterations in DCs to promote IL-17 and lung pathologyR01HL127805 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2016 to 2018
$1.5M
NHLBI NIH HHS R01 HL119682NHLBI NIH HHS R01 HL127805NIAID NIH HHS R01 AI117229NIAID NIH HHS T32 AI007413NIGMS NIH HHS R25 GM086262
6 · The paper itself

Abstract

Hematopoietic stem cell transplant (HSCT) treats or cures a variety of hematological and inherited disorders. Unfortunately, patients who undergo HSCT are susceptible to infections by a wide array of opportunistic pathogens. Pseudomonas aeruginosa bacteria can have life-threatening effects in HSCT patients by causing lung pathology that has been linked to high levels of the potent pro-inflammatory cytokine, interleukin-1β (IL-1β). Using a murine bone marrow transplant (BMT) model, we show that overexpression of prostaglandin E

Indexed as

Hematopoietic Stem Cell TransplantationAnimalsCells, CulturedCyclic AMPDinoprostoneDisease Models, AnimalHumansIndomethacinInterleukin-1betaLung InjuryMacrophages, AlveolarMaleMiceMice, Inbred C57BLPostoperative ComplicationsPseudomonas aeruginosaCyclic AMPDinoprostoneIndomethacinInterleukin-1betaReceptors, Prostaglandin E, EP2 Subtype

Identifiers

PMID28589946
PMCPMC5720939
OpenAlexW2622653999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.