Evidence map›Paper›PMID 28589927›Full record

ArticleNature communications2017

The CaMKII holoenzyme structure in activation-competent conformations.

Janette B Myers, Vincent Zaegel, Steven J Coultrap, Adam P Miller, K Ulrich Bayer, Steve L Reichow

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Article
  2. Article
  3. Structure-informed engineering of plant-microbe interactions.The Plant journal : for cell and molecular biology · 2026
    Review
  4. A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases.Chembiochem : a European journal of chemical biology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Widely Used CaMKII Regulatory Segment Mutations Cause Tight Actinin Binding and Dendritic Spine Enlargement in Unstimulated Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Janette B MyersDepartment of Chemistry, Portland State University, Portland, Oregon 97021, USA.
Vincent ZaegelDepartment of Pharmacology, University of Colorado, Aurora, Colorado 80045, USA.
Steven J CoultrapDepartment of Pharmacology, University of Colorado, Aurora, Colorado 80045, USA.
Adam P MillerDepartment of Chemistry, Portland State University, Portland, Oregon 97021, USA.
K Ulrich BayerDepartment of Pharmacology, University of Colorado, Aurora, Colorado 80045, USA.
Steve L ReichowDepartment of Chemistry, Portland State University, Portland, Oregon 97021, USA.

Funding

ZEBRAFISH TRANSGENIC CORE - ROCKY MOUNTAIN NEUROLOGICAL DISORDERS CORE CENTERP30NS048154 · NINDS · UNIVERSITY OF COLORADO DENVER · PI RIBERA, ANGELES BADELL · 2004 to 2020
$10.1M
CaMKII substrate-selection in opposing forms of synaptic plasticityR01NS081248 · NINDS · UNIVERSITY OF COLORADO DENVER · PI K. Ulrich Bayer · 2013 to 2026
$4.9M
NINDS NIH HHS P30 NS048154NINDS NIH HHS R01 NS081248
6 · The paper itself

Abstract

The Ca

Indexed as

AnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Enzyme ActivationFluorescence Resonance Energy TransferHumansMicroscopy, ElectronModels, MolecularMutationPhosphorylationProtein ConformationProtein DomainsProtein MultimerizationRatsCalcium-Calmodulin-Dependent Protein Kinase Type 2CAMK2A protein, human

Identifiers

PMID28589927
PMCPMC5467236

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.