Evidence map›Paper›PMID 28589858›Full record

ArticleBMC genomics2017

Statistical analysis of fractionation resistance by functional category and expression.

Eric C H Chen, Annie Morin, Jean-Hugues Chauchat, David Sankoff

Abstract read
In one paragraph

Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eric C H ChenDepartment of Biology, University of Ottawa, 30 Marie Curie, Ottawa, K1N 6N5, Canada.
Annie MorinDepartment of Computer Science, Université de Rennes 1, Rennes Cedex, 69676, France.
Jean-Hugues ChauchatLaboratoire ERIC-Lyon2, Université de Lyon 2, Bron Cedex Cedex, 69676, France.
David SankoffDepartment of Mathematics and Statistics, 585 King Edward, Ottawa, K1N 6N5, Canada. sankoff@uottawa.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current literature establishes the importance of gene functional category and expression in promoting or suppressing duplicate gene loss after whole genome doubling in plants, a process known as fractionation. Inspired by studies that have reported gene expression to be the dominating factor in preventing duplicate gene loss, we analyzed the relative effect of functional category and expression.

methodsWe use multivariate methods to study data sets on gene retention, function and expression in rosids and asterids to estimate effects and assess their interaction.

resultsOur results suggest that the effect on duplicate gene retention fractionation by functional category and expression are independent and have no statistical interaction.

conclusionIn plants, functional category is the more dominant factor in explaining duplicate gene loss.

Indexed as

Gene Expression ProfilingGene DosageMolecular Sequence AnnotationStatistics as TopicAngiospermsExpression levelGene lossGene ontologyWhole genome duplication

Identifiers

PMID28589858
PMCPMC5461532

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.