Evidence map›Paper›PMID 28589254›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

Characterisation of malignant peripheral nerve sheath tumours in neurofibromatosis-1 using heterogeneity analysis of

Gary J R Cook, Eitan Lovat, Muhammad Siddique, Vicky Goh, Rosalie Ferner, Victoria S Warbey

Abstract readEvaluation Study
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Diagnostic value ofJournal of neuro-oncology · 2022
    Article
  7. Review
  8. Abdominal radiology (New York) · 2021
    Article
  9. PET/MRI Improves Management of Children with Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Review
  10. Article
  11. Observational
  12. Article
  13. Treatment of malignant peripheral nerve sheath tumors in pediatric NF1 disease.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Review
  14. Article
  15. What can artificial intelligence teach us about the molecular mechanisms underlying disease?European journal of nuclear medicine and molecular imaging · 2019
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gary J R CookCancer Imaging Department, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, SE1 7EH, UK. gary.cook@kcl.ac.uk.
Eitan LovatGuy's, Kings and St Thomas' Medical School, King's College London, London, UK.
Muhammad SiddiqueCancer Imaging Department, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, SE1 7EH, UK.
Vicky GohCancer Imaging Department, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, SE1 7EH, UK.
Rosalie FernerNational Neurofibromatosis Service, Department of Neurology, Guys & St Thomas' NHS Foundation Trust, London, UK.
Victoria S WarbeyCancer Imaging Department, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, SE1 7EH, UK.

Funding

Cancer Research UK 16463Cancer Research UK C1519/A16463
6 · The paper itself

Abstract

purposeMeasurement of heterogeneity in

methods

resultsThere was a significant difference between benign and malignant tumours for all six first-order parameters (at 1.5 and 4 h; p < 0.0001), for second-order entropy (only at 4 h) and for all high-order features (at 1.5 h and 4 h, except contrast at 4 h; p < 0.0001-0.047). Similarly, the area under the receiver operating characteristic curves was high (0.669-0.997, p < 0.05) for the same features as well as 1.5-h second-order entropy. No first-, second- or high-order feature performed better than maximum SUV (SUVmax) at differentiating benign from malignant tumours.

conclusions

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAdolescentAdultAgedChildDiagnosis, DifferentialFemaleHumansLimit of DetectionMaleMiddle AgedNerve Sheath NeoplasmsNeurofibromatosis 1Positron Emission Tomography Computed TomographyFluorodeoxyglucose F18Radiopharmaceuticals18F-FDG petHeterogeneityMalignant peripheral nerve sheath tumourNeurofibromatosis-1Standardised uptake value

Identifiers

PMID28589254
PMCPMC5644685

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.