SynthesisSleep & breathing = Schlaf & Atmung2018
A systematic review and dose-response meta-analysis of sleep duration and the occurrence of cognitive disorders.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Sleep disturbances and risk of Alzheimer's disease: a systematic review and meta-analysis of longitudinal cohort studies.Alzheimer's research & therapy · 2026Pooled it
- Sleep duration, sleep efficiency, and amyloid β among cognitively healthy later-life adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Umbrella review and Delphi study on modifiable factors for dementia risk reduction.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Sleep duration and health outcomes: an umbrella review.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Sleep Duration/Quality With Health Outcomes: An Umbrella Review of Meta-Analyses of Prospective Studies.Frontiers in medicine · 2021Pooled it
- The Potential Contribution of Chronic Pain and Common Chronic Pain Conditions to Subsequent Cognitive Decline, New Onset Cognitive Impairment, and Incident Dementia: A Systematic Review and Conceptual Model for Future Research.Journal of Alzheimer's disease : JAD · 2020Pooled it
- Wife-husband differences in the associations between sleep durations and global cognition among middle-aged and older married couples in China: a longitudinal dyadic analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Associations Between 24 h Movement Behaviours and Cognitive Abilities in Slovak Adolescents: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Polygenic score for sleep duration in relation to the risk of Alzheimer's disease: results from the UK biobank.Frontiers in dementia · 2026Article
- Genetic disparities in sleep traits and human capital development: A 25-year study in Finnish population-based cohorts.Scandinavian journal of work, environment & health · 2026Article
- Association between sleep duration, depression and cognitive decline trajectories: findings from a prospective cohort study in China.BMC psychiatry · 2025Article
- Associations of physical activity, sedentary behavior, and sleep patterns with cognitive function among middle-aged and older adults.Journal of activity, sedentary and sleep behaviors · 2025Article
- Sleep duration and quality trajectories during the early days of the COVID-19 pandemic: a Canadian nationally representative study.BMC public health · 2025Article
- Associations of nighttime sleep, midday napping, and physical activity with all-cause mortality in older adults: the Seniors-ENRICA cohorts.GeroScience · 2025Article
- Mendelian randomization study of self-reported long sleep duration, short sleep duration, and insomnia and cognitive function.PloS one · 2025Article
- Sleep duration and cognitive function among rural older adults in China: A population-based study.PloS one · 2025Article
- Nonlinear associations of depression and sleep duration with cognitive impairment in older adults with hypertension: findings from a national survey.Frontiers in aging neuroscience · 2025Article
- Association of Sleep Disturbances With Prevalent and Incident Motoric Cognitive Risk Syndrome in Community-Residing Older Adults.Neurology · 2024Article
- Association between nighttime sleep duration, nap time, and mild cognitive impairment in Chinese older adults: a cross-sectional study.BMC public health · 2024Article
- Military Values, Military Virtues, and Vulnerable Narcissism among Cadets of the Swiss Armed Forces-Results of a Cross-Sectional Study.European journal of investigation in health, psychology and education · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious researches have shown inconsistent findings on the relationship between sleep duration and cognitive disorders (including cognitive decline, dementia, Alzheimer's disease, and cognitive impairment). Furthermore, the possible dose-response association of sleep duration and cognitive disorders is still not clear.
methodsTwo databases (PubMed and Embase) were searched for relevant studies from inception to May 4, 2016. We used the generic inverse-variance method to combine the outcomes with a random-effects model for the association between sleep duration (the shortest or longest vs. middle category) and cognitive disorders. Additionally, we used the generalized least-squares trend estimation model to estimate the potential dose-response association.
resultsFinally, nine eligible cohort studies involving 22,187 participants were included in the present systematic review and meta-analysis. Compared with the middle category, both short and long sleep duration were accompanied by a significantly higher incident risk of cognitive disorders, and the relative risks (RRs) and 95% confidence intervals (CIs) were 1.34 (1.15, 1.56) and 1.21 (1.06, 1.39), respectively. Moreover, an approximately "U-shaped" dose-response relationship was observed. Stratified analyses showed that the association between short sleep duration and cognitive disorders was more robust in the subgroup of the measurement of sleep duration based on self-report.
conclusionsThe lowest incident risk of cognitive disorders was found at the sleep duration of 7-8 h per day. The present study includes a small number of studies, and the study participants mostly consist of Caucasian population. In the future, researches are also warranted to confirm the association in different groups of people.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.