Evidence map›Paper›PMID 28589136›Full record

ArticleBioMed research international2017

Low Molecular Weight Heparin Nebulization Attenuates Acute Lung Injury.

Nianlin Xie, Menglei Huan, Feng Tian, Zhongping Gu, Xiaofei Li

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nianlin XieDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038, China.
Menglei HuanDepartment of Pharmaceutics, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China.
Feng TianDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038, China.
Zhongping GuDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038, China.ORCID 0000-0002-3564-0943
Xiaofei LiDepartment of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038, China.ORCID 0000-0001-7828-0274
Air Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs acute lung injury (ALI) caused high mortality rate, it is important to explore the protection and treatment of ALI. The aim of the current study is to evaluate the effect of low molecular weight heparin (LMWH) nebulization on attenuating acute lung injury and the associated mechanism.

methodsThe arterial blood gas, total protein content in bronchoalveolar lavage fluid, lung wet/dry weight ratio, malondialdehyde (MDA) content, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activity, and Akt phosphorylation were evaluated after the ALI rabbits were treated with or without LMWH nebulization.

resultsPaO

conclusionsLMWH nebulization treatment can relieve the traumatic ALI in rabbits and inhibit oxidative stress possibly by suppressing the Akt phosphorylation.

Indexed as

Acute Lung InjuryAdministration, InhalationAnimalsDisease Models, AnimalGlutathione PeroxidaseHeparin, Low-Molecular-WeightMalondialdehydeNebulizers and VaporizersRabbitsSuperoxide DismutaseGlutathione PeroxidaseHeparin, Low-Molecular-WeightMalondialdehydeSuperoxide Dismutase

Identifiers

PMID28589136
PMCPMC5447277
OpenAlexW2616349468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.