ReviewFrontiers in cardiovascular medicine2017
Myocardial Architecture, Mechanics, and Fibrosis in Congenital Heart Disease.
Review in Frontiers in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 55 citations in OpenAlex.
- Constitutive discovery in the living human heart.bioRxiv : the preprint server for biology · 2026Article
- Genetic drivers of congenital cardiac fibrosis.Communications biology · 2026Review
- Heart Failure in Adult Congenital Heart Disease.Methodist DeBakey cardiovascular journal · 2026Review
- Article
- Endocardial Fibrosis Elastosis: Long-Standing Mystery and Promising Therapy.JACC. Basic to translational science · 2025Article
- Electrically conductive biopolymer-based hydrogels and fibrous materials fabricated using 3D printing and electrospinning for cardiac tissue engineering.Bioactive materials · 2025Review
- Genetic test results and one-year developmental outcomes of fetuses with congenital heart disease.Frontiers in pediatrics · 2025Article
- The assessment of left ventricular diastolic function: guidance and recommendations from the British Society of Echocardiography.Echo research and practice · 2024Review
- The Right Heart in Congenital Heart Disease.Current heart failure reports · 2023Review
- Use of Cardiovascular Magnetic Resonance for Risk Stratification in Repaired Tetralogy of Fallot.CJC pediatric and congenital heart disease · 2023Review
- A Correspondence-Based Network Approach for Groupwise Analysis of Patient-Specific Spatiotemporal Data.Annals of biomedical engineering · 2023Article
- Electrical and Structural Insights into Right Ventricular Outflow Tract Arrhythmogenesis.International journal of molecular sciences · 2023Review
- Clinical Characteristics and Outcomes in Adults With Moderate-to-Severe Complexity Congenital Heart Disease Undergoing Palliation or Surgical Repair.CJC pediatric and congenital heart disease · 2023Article
- Transverse and longitudinal right ventricular fractional parameters derived from four-chamber cine MRI are associated with right ventricular dysfunction etiology.Scientific reports · 2023Article
- Heart Failure with Preserved Ejection Fraction in Children.Pediatric cardiology · 2023Review
- Feasibility of gray-blood late gadolinium enhancement evaluation in young patients with congenital and acquired heart disease.Frontiers in cardiovascular medicine · 2023Article
- Chagas Heart Disease: Beyond a Single Complication, from Asymptomatic Disease to Heart Failure.Journal of clinical medicine · 2022Review
- Right ventricular structure and function after novel repair of common arterial trunk.International journal of cardiology. Congenital heart disease · 2022Article
- Scale space detector for analyzing spatiotemporal ventricular contractility and nuclear morphogenesis in zebrafish.iScience · 2022Article
- Early post-operative benefits of a pulmonary valve-sparing strategy during Fallot repair.International journal of cardiology. Congenital heart disease · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Congenital heart disease (CHD) is the most common category of birth defect, affecting 1% of the population and requiring cardiovascular surgery in the first months of life in many patients. Due to advances in congenital cardiovascular surgery and patient management, most children with CHD now survive into adulthood. However, residual and postoperative defects are common resulting in abnormal hemodynamics, which may interact further with scar formation related to surgical procedures. Cardiovascular magnetic resonance (CMR) has become an important diagnostic imaging modality in the long-term management of CHD patients. It is the gold standard technique to assess ventricular volumes and systolic function. Besides this, advanced CMR techniques allow the acquisition of more detailed information about myocardial architecture, ventricular mechanics, and fibrosis. The left ventricle (LV) and right ventricle have unique myocardial architecture that underpins their mechanics; however, this becomes disorganized under conditions of volume and pressure overload. CMR diffusion tensor imaging is able to interrogate non-invasively the principal alignments of microstructures in the left ventricular wall. Myocardial tissue tagging (displacement encoding using stimulated echoes) and feature tracking are CMR techniques that can be used to examine the deformation and strain of the myocardium in CHD, whereas 3D feature tracking can assess the twisting motion of the LV chamber. Late gadolinium enhancement imaging and more recently T1 mapping can help in detecting fibrotic myocardial changes and evolve our understanding of the pathophysiology of CHD patients. This review not only gives an overview about available or emerging CMR techniques for assessing myocardial mechanics and fibrosis but it also describes their clinical value and how they can be used to detect abnormalities in myocardial architecture and mechanics in CHD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.