Evidence map›Paper›PMID 28589095›Full record

ReviewFrontiers in cellular and infection microbiology2017

Diversity and Versatility of Phagocytosis: Roles in Innate Immunity, Tissue Remodeling, and Homeostasis.

Justin J Lim, Sergio Grinstein, Ziv Roth

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 212 citations in OpenAlex.

  1. Monocytes in pneumonia: Functional plasticity and innate memory (Review).International journal of molecular medicine · 2026
    Review
  2. Article
  3. Microbiology spectrum · 2026
    Article
  4. Review
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  6. A critical signaling role for diacylglycerol in phagocytosis ofbioRxiv : the preprint server for biology · 2026
    Article
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Justin J LimProgram in Cell Biology, Hospital for Sick ChildrenToronto, ON, Canada.
Sergio GrinsteinProgram in Cell Biology, Hospital for Sick ChildrenToronto, ON, Canada.
Ziv RothProgram in Cell Biology, Hospital for Sick ChildrenToronto, ON, Canada.
Hospital for Sick Children · CA

Funding

CIHR FDN143202
6 · The paper itself

Abstract

Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role in innate immunity by eliminating pathogenic bacteria, fungi and malignant cells, and contribute to adaptive immunity by presenting antigens to lymphocytes. In addition, phagocytes play a part in tissue remodeling and maintain overall homeostasis by disposing of apoptotic cells, a task shared by non-professional phagocytes, often of epithelial origin. This functional versatility is supported by a vast array of receptors capable of recognizing a striking variety of foreign and endogenous ligands. Here we present an abbreviated overview of the different types of phagocytes, their varied modes of signaling and particle engulfment, and the multiple physiological roles of phagocytosis.

Indexed as

Adaptive ImmunityAntigen PresentationCell Line, TumorHomeostasisHumansImmunity, InnateInflammationLymphocytesMaleNeurogenesisNeutrophilsPhagocytesPhagocytosisPhagosomesSertoli CellsSignal Transductionmacrophageneutrophilphagocytephagocytosisphagosome

Identifiers

PMID28589095
PMCPMC5440456
OpenAlexW2617955321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.