Evidence map›Paper›PMID 28588992›Full record

ArticleBMJ global health2017

Introducing rapid tests for malaria into the retail sector: what are the unintended consequences?

Eleanor Hutchinson, Coll Hutchison, Sham Lal, Kristian Hansen, Miriam Kayendeke, Christine Nabirye, Pascal Magnussen, Siân E Clarke, Anthony Mbonye, Clare I R Chandler

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ global health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01194557 (Introducing Rapid Diagnostic Tests Into the Private Health Sector in Uganda), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01194557 nacompletednot on this map

Introducing Rapid Diagnostic Tests Into the Private Health Sector in Uganda: a Randomised Trial Among Registered Drug Shops to Evaluate Impact on Antimalarial Drug Use

TypeinterventionalSponsorDBL -Institute for Health Research and DevelopmentRan2010 to 2012Enrolled2,600ConditionsFever, Malaria, Diagnosis, ReferralArmsRapid diagnostic test, Lumartem
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Eleanor HutchinsonDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Coll HutchisonDepartment of Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, UK.
Sham LalDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Kristian HansenDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Miriam KayendekeThe Act 2 Project, Kampala, Uganda.
Christine NabiryeInfectious Disease Research Collaboration, Kampala, Uganda.
Pascal MagnussenDepartment of International Health, Immunology and Microbiology, Centre for Medical Parasitology & Institute for Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, University of Copenhagen, Kobenhavn, Denmark.
Siân E ClarkeFaculty of Infectious and Tropical Diseases, Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-3829-9584
Anthony MbonyeMinistry of Health, Kampala, Uganda.
Clare I R ChandlerDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBInfectious Diseases Research Collaboration · UGMinistry of Health · UGUniversity of Copenhagen · DK

Funding

Medical Research Council MR/N003810/1Wellcome Trust
6 · The paper itself

Abstract

The observation that many people in Africa seek care for febrile illness in the retail sector has led to a number of public health initiatives to try to improve the quality of care provided in these settings. The potential to support the introduction of rapid diagnostic tests for malaria (mRDTs) into drug shops is coming under increased scrutiny. Those in favour argue that it enables the harmonisation of policy around testing and treatment for malaria and maintains a focus on market-based solutions to healthcare. Despite the enthusiasm among many global health actors for this policy option, there is a limited understanding of the consequences of the introduction of mRDTs in the retail sector. We undertook an interpretive, mixed methods study with drug shop vendors (DSVs), their clients and local health workers to explore the uses and interpretations of mRDTs as they became part of daily practice in drug shops during a trial in Mukono District, Uganda. This paper reports the unintended consequences of their introduction. It describes how the test engendered trust in the professional competence of DSVs; was misconstrued by clients and providers as enabling a more definitive diagnosis of disease in general rather than malaria alone; that blood testing made drug shops more attractive places to seek care than they had previously been; was described as shifting treatment-seeking behaviour away from formal health centres and into drug shops; and influenced an increase in sales of medications, particularly antibiotics. TRIAL REGISTRATION NUMBER: NCT01194557; Results.

Identifiers

PMID28588992
PMCPMC5321379
OpenAlexW2577639839

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.