ArticleUnited European gastroenterology journal2017
Laparoscopic versus open appendectomy in adults and children: A meta-analysis of randomized controlled trials.
Article in United European gastroenterology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 7 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Meta-analysis of the clinical efficacy of laparoscopic appendectomy in the treatment of acute appendicitis.World journal of emergency surgery : WJES · 2022Pooled it
- Discordant outcomes of laparoscopic versus open appendectomy for suspected appendicitis during pregnancy in published meta-analyses: an overview of systematic reviews.Surgical endoscopy · 2020Pooled it
- Global incidence of surgical site infection after appendectomy: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Laparoscopic versus open appendectomy in pediatric patients with complicated appendicitis: a meta-analysis.Surgical endoscopy · 2019Pooled it
- Laparoscopy versus open appendectomy for elderly patients, a meta-analysis and systematic review.BMC surgery · 2019Pooled it
- Laparoscopic Repair for Perforated Peptic Ulcer Disease Has Better Outcomes Than Open Repair.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Pooled it
- Laparoscopic versus open surgery for suspected appendicitis.The Cochrane database of systematic reviews · 2018Pooled it
- Single versus double Hem-o-lok clips to secure the apendiceal stump during laparoscopic appendectomy: a prospective randomized multicentric clinical trial.Langenbeck's archives of surgery · 2024Trial
- A randomized clinical trial of technical modifications of appendix stump closure during laparoscopic appendectomy for uncomplicated acute appendicitis.BMC surgery · 2021Trial
- The influence of the different forms of appendix base closure on patient outcome in laparoscopic appendectomy: a randomized trial.Surgical endoscopy · 2018Trial
- Contemporary National Inpatient Trends in appendectomy utilization and operative approach in the United States, 2016-2022.Surgery open science · 2026Article
- Endoscopic direct-vision therapy for acute uncomplicated appendicitis: a retrospective study.Frontiers in medicine · 2026Article
- Laparoscopic versus open appendectomy for acute appendicitis in Sub-Saharan Africa.Annals of medicine and surgery (2012) · 2026Article
- Minimally Invasive Surgical Techniques in the Treatment of Appendicitis: A Narrative Review.Cureus · 2025Review
- Article
- Conversion Rates and Outcomes of Laparoscopic Appendectomy in Complicated Appendicitis: A Retrospective Study.Cureus · 2025Article
- Inflammatory Metabolic Index and Metabolic-Inflammatory Stress Index as New Biomarkers for Complicated and Perforated Acute Appendicitis.Journal of clinical medicine · 2025Article
- Laparoscopic appendectomy as the gold standard: What role remains for open surgery, conversion, and disease severity? : An analysis of 32,000 cases with appendicitis in Germany.World journal of emergency surgery : WJES · 2025Observational
- Acute appendicitis and its treatment: a historical overview.International journal of colorectal disease · 2025Article
- Is Routine Group and Save Sampling Necessary for Emergency Laparoscopic Appendicectomy?Cureus · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to evaluate the differences of laparoscopic appendectomy (LA) versus open appendectomy (OA) in adults and children.
methodsRandomized controlled trials (RCTs) comparing LA and OA in adults and children between January 1992-March 2016 were included in this study. A meta-analysis was performed to evaluate wound infection, intra-abdominal abscess, postoperative complications, reoperation rate, operation time, postoperative stay, and return to normal activity.
resultThirty-three studies including 3642 patients (1810 LA, 1832 OA) were included. Compared with OA, LA in adults was associated with lower incidence of wound infection, fewer postoperative complications, shorter postoperative stay, and earlier return to normal activity, but a longer operation time. There was no difference in levels of intra-abdominal abscess and reoperation between the groups. Subgroup analysis in children did not reveal significant differences between the two techniques in wound infection, postoperative complications, postoperative stay, and return to normal activity.
conclusionLA in adults is worth recommending as an effective and safe procedure for acute appendicitis, and further high-quality randomized trials comparing the two techniques in children are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.