Evidence map›Paper›PMID 28588881›Full record

ArticleUnited European gastroenterology journal2017

Endoscopic classification of the papilla of Vater. Results of an inter- and intraobserver agreement study.

E Haraldsson, L Lundell, F Swahn, L Enochsson, J M Löhr, U Arnelo, Scandinavian Association for Digestive Endoscopy (SADE) Study Group of Endoscopic Retrograde Cholangio-Pancreaticography

3 registry-linked trialsAbstract read
In one paragraph

Article in United European gastroenterology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04492124 unknown statusnot on this mapstarted 2020, after this paper: background citation

Influence of Vater's Ampulla Morphology on Biliary Cannulation Rate, Complications and Advanced Biliary Cannulation Techniques

Typeobservational_patient_registrySponsorUniversity of MinhoRan2020 to 2022Enrolled400ConditionsPancreatitis
NCT05068739 nacompletednot on this mapstarted 2021, after this paper: background citation

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

TypeinterventionalSponsorDuzce UniversityRan2021 to 2022Enrolled80ConditionsBiliary Disease, Common Bile Duct Calculi, Biliary Stricture, Malignant Hepatobiliary NeoplasmArmsPA-EMR, NKF
NCT05336630 nacompletednot on this mapstarted 2022, after this paper: background citation

SOCCER: Study Of forCeps Cannulation During ERcp

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2022 to 2024Enrolled152ConditionsPost-ERCP Acute PancreatitisArmsForceps
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Tip palpation of the intraduodenal biliary segment for needle-knife fistulotomy.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
    Review
  13. Article
  14. Rescue cannulation techniques in difficult biliary access-A comprehensive review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

E HaraldssonDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
L LundellDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
F SwahnDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
L EnochssonDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
J M LöhrDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
U ArneloDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Scandinavian Association for Digestive Endoscopy (SADE) Study Group of Endoscopic Retrograde Cholangio-Pancreaticography

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany endoscopists acknowledge that the appearance of the papilla of Vater seems to affect biliary cannulation. To assess the association between the macroscopic appearance of the papilla and biliary cannulation and other related clinical issues, a system is needed to define the appearance of the papilla.

objectiveThe purpose of this study was to validate an endoscopic classification of the papilla of Vater by assessing the interobserver and intraobserver agreements among endoscopist with varying experience.

methodsAn endoscopic classification, based on pictures captured from 140 different papillae, containing four types of papillae was proposed. The four types are (a) Type 1: regular papilla, no distinctive features, 'classic appearance'; (b) Type 2: small papilla, often flat, with a diameter ≤ 3 mm (approximately 9 Fr); (c) Type 3: protruding or pendulous papilla, a papilla that is standing out, protruding or bulging into the duodenal lumen or sometimes hanging down, pendulous with the orifice oriented caudally; and (d) Type 4: creased or ridged papilla, where the ductal mucosa seems to extend distally, rather out of the papillary orifice, either on a ridge or in a crease. To assess the level of interobserver agreement, a web-based survey was sent out to 18 endoscopists, containing 50 sets of still images of the papilla, distributed between the four different types. Three months later a follow-up survey, with images from the first survey was sent to the same endoscopists.

resultsInterobserver agreement was substantial (κ = 0.62, 95% confidence interval (CI) 0.58-0.65) and were similar for both experts and non-experts. The intraobserver agreement assessed with the second survey was also substantial (κ = 0.66, 95% CI 0.59-0.72).

conclusionThe proposed endoscopic classification of the papilla of Vater seems to be easy to use, irrespective of the level of experience of the endoscopist. It carries a substantial inter- and intraobserver agreement and now the clinical relevance of the four different papilla types awaits to be determined.

Indexed as

Duodenoscopyendoscopic classificationendoscopic retrograde cholangio-pancreaticographyinterobserver agreementintraobserver agreementpapilla of Vater

Identifiers

PMID28588881
PMCPMC5446150

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.