Evidence map›Paper›PMID 28588778›Full record

ArticleMolecular and clinical oncology2017

Rexin-G

Seth Kim, Noah Federman, Erlinda M Gordon, Frederick L Hall, Sant P Chawla

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04091295 (BLESSED), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04091295 availablenot on this map

BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast

Typeexpanded_accessSponsorAveni FoundationConditionsPancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor), ChondrosarcomaArmsDNG64-CAR-V
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Haematologica · 2020
    Article
  8. Article
  9. Gene Therapy Leaves a Vicious Cycle.Frontiers in oncology · 2019
    Review
  10. Exploiting Oncogenic Drivers along theMolecular therapy oncolytics · 2018
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seth KimSarcoma Oncology Center/Cancer Center of Southern California, Santa Monica, CA 90403, USA.
Noah FedermanDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, Mattel Children's Hospital at UCLA, Los Angeles, CA 90095, USA.
Erlinda M GordonSarcoma Oncology Center/Cancer Center of Southern California, Santa Monica, CA 90403, USA.
Frederick L HallCounterpoint Biomedica LLC, Santa Monica, CA 90403, USA.
Sant P ChawlaSarcoma Oncology Center/Cancer Center of Southern California, Santa Monica, CA 90403, USA.
Sarcoma Oncology Center · USMattel Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soft tissue sarcoma is a rare neoplasm of mesenchymal origin, accounting for only ~1% of all adult cancers and consisting of 75 histological subtypes. In the present report, the unique case of a 14 year-old female with metastatic malignant peripheral nerve sheath tumor (formerly, malignant melanotic schwannoma) of the parotid gland, who experienced a durable response and sustained tumor control with Rexin-G

Indexed as

cell cycle controlmetastatic sarcomatargeted gene therapy vector

Identifiers

PMID28588778
PMCPMC5451875
OpenAlexW2607810319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.