Evidence map›Paper›PMID 28588622›Full record

ArticleStem cells international2017

Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1.

Josephine Wesely, Marlene Steiner, Frank Schnütgen, Manuel Kaulich, Michael A Rieger, Martin Zörnig

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Josephine WeselyGeorg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Paul-Ehrlich-Strasse 42-44, 60596 Frankfurt/Main, Germany.
Marlene SteinerGeorg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Paul-Ehrlich-Strasse 42-44, 60596 Frankfurt/Main, Germany.ORCID 0000-0002-0365-5120
Frank SchnütgenLOEWE Center for Cell and Gene Therapy Frankfurt and Department for Medicine, Hematology/Oncology, Goethe University Hospital Frankfurt/Main, 60590 Frankfurt/Main, Germany.
Manuel KaulichInstitute of Biochemistry II, Goethe University Frankfurt, 60590 Frankfurt/Main, Germany.
Michael A RiegerLOEWE Center for Cell and Gene Therapy Frankfurt and Department for Medicine, Hematology/Oncology, Goethe University Hospital Frankfurt/Main, 60590 Frankfurt/Main, Germany.ORCID 0000-0002-4158-5872
Martin ZörnigGeorg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Paul-Ehrlich-Strasse 42-44, 60596 Frankfurt/Main, Germany.ORCID 0000-0002-6347-4962
Goethe University Frankfurt · DEGeorg Speyer Haus · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcriptional regulator far upstream binding protein 1 (FUBP1) is essential for fetal and adult hematopoietic stem cell (HSC) self-renewal, and the constitutive absence of FUBP1 activity during early development leads to embryonic lethality in homozygous mutant mice. To investigate the role of FUBP1 in murine embryonic stem cells (ESCs) and in particular during differentiation into hematopoietic lineages, we generated

Identifiers

PMID28588622
PMCPMC5447289
OpenAlexW2616357914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.