Evidence map›Paper›PMID 28588500›Full record

ArticleFrontiers in physiology2017

Temporal Expression Patterns of Clock Genes and Aquaporin 5/Anoctamin 1 in Rat Submandibular Gland Cells.

Ryouichi Satou, Masaki Sato, Maki Kimura, Yoichi Ishizuka, Masakazu Tazaki, Naoki Sugihara, Yoshiyuki Shibukawa

Abstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Aquaporin-5 Dynamic Regulation.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Circadian clocks in the digestive system.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryouichi SatouDepartment of Epidemiology and Public Health, Tokyo Dental CollegeTokyo, Japan.
Masaki SatoDepartment of Physiology, Tokyo Dental CollegeTokyo, Japan.
Maki KimuraDepartment of Physiology, Tokyo Dental CollegeTokyo, Japan.
Yoichi IshizukaDepartment of Epidemiology and Public Health, Tokyo Dental CollegeTokyo, Japan.
Masakazu TazakiDepartment of Physiology, Tokyo Dental CollegeTokyo, Japan.
Naoki SugiharaDepartment of Epidemiology and Public Health, Tokyo Dental CollegeTokyo, Japan.
Yoshiyuki ShibukawaDepartment of Physiology, Tokyo Dental CollegeTokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian rhythms are essential for health and regulate various physiological functions. These rhythms are regulated by a negative-feedback loop involving clock genes in the suprachiasmatic nucleus (SCN) and peripheral tissues. The rate of secretion of salivary substances, ions, and water follows a circadian rhythm, however, the relationship between the molecular mechanism of salivary secretion and peripheral circadian rhythm is not yet clear. Anoctamin 1 (ANO1, also known as TMEM16A) and Aquaporin 5 (AQP5) play an important role in the transport of ions and water in the submandibular glands (SGs). We examined the interaction between the rhythmic expression pattern of the clock genes,

Indexed as

aquaporinchloride channelcircadian rhythmclock genesecretiontransport

Identifiers

PMID28588500
PMCPMC5440558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.