ArticleFrontiers in aging neuroscience2017
Age-Related Differences in Dynamic Interactions Among Default Mode, Frontoparietal Control, and Dorsal Attention Networks during Resting-State and Interference Resolution.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An Activation Likelihood Estimation Meta-Analysis of Specific Functional Alterations in Dorsal Attention Network in Mild Cognitive Impairment.Frontiers in neuroscience · 2022Pooled it
- From rest to focus: pharmacological modulation of the relationship between resting state dorsal attention network dynamics and task-based brain activation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Trial
- Lower engagement of cognitive control in children on ChatGPT.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Default mode network functional connectivity is associated with intention interference in healthy aging.Brain imaging and behavior · 2026Article
- Article
- Effects of aging on the mechanisms of dynamic integration between the default mode network and other brain networks: evidence based on fMRI data with natural stimulation.Brain imaging and behavior · 2026Article
- Cognitive ability in childhood predicts adolescent structural and functional brain development: A longitudinal study.Developmental cognitive neuroscience · 2026Article
- Brain resting state functional connectivity changes with aerobic exercise, and mindfulness: A narrative review.Sports medicine and health science · 2026Review
- Bilateral Angular Gyrus 810-nm Transcranial Near-Infrared Stimulation Reshapes Brain Network: Ameliorate Alzheimer's Disease Cognitive Deficits.BME frontiers · 2026Article
- Gender- and domain-specific effects of a 6-month multidimensional exercise program on attention and verbal fluency in physically inactive older adults.Frontiers in aging · 2026Article
- Network segregation is associated with processing speed in the cognitively healthy oldest-old.eLife · 2025Article
- Infraslow Dynamic Patterns in Human Cortical Networks Track a Spectrum of External to Internal Attention.Human brain mapping · 2025Article
- Revealing the Spatial Pattern of Brain Hemodynamic Sensitivity to Healthy Aging through Sparse Dynamic Causal Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dedifferentiation of caudate functional organization is linked to reduced D1 dopamine receptor availability and poorer memory function in aging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Advances in the fMRI analysis of the default mode network: a review.Brain structure & function · 2024Review
- Brain activations elicited during task-switching generalize beyond the task: A partial least squares correlation approach to combine fMRI signals and cognition.Human brain mapping · 2024Article
- Changes in Spatiotemporal Dynamics of Default Network Oscillations between 19 and 29 Years of Age.Brain sciences · 2024Article
- Infraslow dynamic patterns in human cortical networks track a spectrum of external to internal attention.bioRxiv : the preprint server for biology · 2024Article
- Longitudinal monitoring of the mouse brain reveals heterogenous network trajectories during aging.Communications biology · 2024Article
- Differential spatial working memory-related functional network reconfiguration in young and older adults.Network neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resting-state fMRI (rs-fMRI) can identify large-scale brain networks, including the default mode (DMN), frontoparietal control (FPN) and dorsal attention (DAN) networks. Interactions among these networks are critical for supporting complex cognitive functions, yet the way in which they are modulated across states is not well understood. Moreover, it remains unclear whether these interactions are similarly affected in aging regardless of cognitive state. In this study, we investigated age-related differences in functional interactions among the DMN, FPN and DAN during rest and the Multi-Source Interference task (MSIT). Networks were identified using independent component analysis (ICA), and functional connectivity was measured during rest and task. We found that the FPN was more coupled with the DMN during rest and with the DAN during the MSIT. The degree of FPN-DMN connectivity was lower in older compared to younger adults, whereas no age-related differences were observed in FPN-DAN connectivity in either state. This suggests that dynamic interactions of the FPN are stable across cognitive states. The DMN and DAN were anti correlated and age-sensitive during the MSIT only, indicating variation in a task-dependent manner. Increased levels of anticorrelation from rest to task also predicted successful interference resolution. Additional analyses revealed that the degree of DMN-DAN anticorrelation during the MSIT was associated to resting cerebral blood flow (CBF) within the DMN. This suggests that reduced DMN neural activity during rest underlies an impaired ability to achieve higher levels of anticorrelation during a task. Taken together, our results suggest that only parts of age-related differences in connectivity are uncovered at rest and thus, should be studied in the functional connectome across multiple states for a more comprehensive picture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.