ArticleFrontiers in aging neuroscience2017
A Life-Long Approach to Physical Activity for Brain Health.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04841668 (Gut-Brain-axis), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can Physical Activity Reduce the Risk of Cognitive Decline in Apolipoprotein e4 Carriers? A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- The Urban Built Environment, Walking and Mental Health Outcomes Among Older Adults: A Pilot Study.Frontiers in public health · 2020Trial
- Midlife physical activity and late-life subjective cognitive complaints in women.The Gerontologist · 2026Article
- Concurrent cognitive and physical training for cognition in men with prostate cancer: a study protocol for a pilot randomized controlled trial.Frontiers in medicine · 2026Article
- Associations of Adherence to the 24hour Movement Guidelines with Depressive Symptoms and Anxiety: the Mediating Role of Physical Fitness.BMC public health · 2025Article
- Move to Remember: The Role of Physical Activity and Exercise in Preserving and Enhancing Cognitive Function in Aging-A Narrative Review.Geriatrics (Basel, Switzerland) · 2025Review
- Effects of physical activity interventions on fundamental movement skills and cognitive function in early childhood: A systematic review and network meta-analysis.Journal of sport and health science · 2025Review
- Physical Activity Monitoring in Children in the 1-Year After 3 or More Days of Invasive Ventilation: Feasibility of Using Accelerometers.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Physical activity as a predictor of fremanezumab response in chronic migraine - the Phy-Fre-Mig study.The journal of headache and pain · 2025Observational
- Cognitive profile in burning mouth syndrome versus mild cognitive impairment: A comparative study.Oral diseases · 2025Article
- The effect of physical exercise with cognitive training on inflammation and Alzheimer's disease biomarkers of Mild Cognitive Impairment patients.Neuroscience applied · 2024Article
- Neurosustainability.Frontiers in human neuroscience · 2024Article
- Risk assessment of low cognitive performance among fishermen's children in Malaysia.Journal of Taibah University Medical Sciences · 2023Article
- Factors associated with physical activity participation among children: a systematic review protocol.Systematic reviews · 2023Article
- Unicorn, Hare, or Tortoise? Using Machine Learning to Predict Working Memory Training Performance.Journal of cognition · 2023Article
- The burden of mild cognitive impairment attributable to physical inactivity in Colombia.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2022Article
- Exploring cognitive and brain oxygenation changes over a 1-year period in physically active individuals with mild cognitive impairment: a longitudinal fNIRS pilot study.BMC geriatrics · 2022Article
- The combined effect of physical activity and fruit and vegetable intake on decreasing cognitive decline in older Taiwanese adults.Scientific reports · 2022Article
- Physical Activity in High School Classrooms: A Promising Avenue for Future Research.International journal of environmental research and public health · 2022Review
- Physical activities and risk of neurodegenerative diseases: A two-sample Mendelian randomization study.Frontiers in aging neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that engaging in lifelong Physical activity (PA) can help delay the onset of many chronic lifestyle related and non-communicable diseases such as cardiovascular disease, type two diabetes, cancer and chronic respiratory diseases. Additionally, growing evidence also documents the importance of PA for brain health, with numerous studies indicating regular engagement in physical activities may be protective against cognitive decline and dementia in late life. Indeed, the link between PA and brain health may be different at each stage of life from childhood, mid-life and late life. Building on this emerging body of multidisciplinary research, this review aims to summarize the current body of evidence linking regular PA and brain health across the lifespan. Specifically, we will focus on the relationship between PA and brain health at three distinct stages of life: childhood and adolescence, mid-life, late life in cognitively healthy adults and later life in adults living with age-related neurodegenerative disorders such as Parkinson's disease (PD) and Alzheimer's disease (AD).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.