Evidence map›Paper›PMID 28588455›Full record

ArticleFrontiers in neural circuits2017

Circuits Regulating Pleasure and Happiness in Bipolar Disorder.

Anton J M Loonen, Ralph W Kupka, Svetlana A Ivanova

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Attention-deficit/hyperactive disorder updates.Frontiers in molecular neuroscience · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Neurobiological mechanisms associated with antipsychotic drug-induced dystonia.Journal of psychopharmacology (Oxford, England) · 2021
    Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anton J M LoonenGroningen Research Institute of Pharmacy, University of GroningenGroningen, Netherlands.
Ralph W KupkaDepartment of Psychiatry, VU University Medical CenterAmsterdam, Netherlands.
Svetlana A IvanovaTomsk National Research Medical Center of the Russian Academy of Sciences, Mental Health Research InstituteTomsk, Russia.
GGZ Westelijk Noord-Brabant · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to our model, the motivation for appetitive-searching vs. distress-avoiding behaviors is regulated by two parallel cortico-striato-thalamo-cortical (CSTC) re-entry circuits that include the core and the shell parts of the nucleus accumbens, respectively. An entire series of basal ganglia, running from the caudate nucleus on one side to the centromedial amygdala on the other side, control the intensity of these reward-seeking and

Indexed as

HappinessAntidepressive AgentsBipolar DisorderHumansModels, BiologicalNerve NetNeural PathwaysPleasureAntidepressive Agentsamygdalabasal gangliabipolar disorderhabenulamechanismneuroplasticitystress

Identifiers

PMID28588455
PMCPMC5439000
OpenAlexW2617526248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.