Evidence map›Paper›PMID 28588439›Full record

ArticleFrontiers in neuroscience2017

DNA Methylation Changes in Intron 1 of

Yuta Yoshino, Yuki Ozaki, Kiyohiro Yamazaki, Tomoko Sao, Yoko Mori, Shinichiro Ochi, Jun-Ichi Iga, Shu-Ichi Ueno

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Profile ofInternational journal of molecular sciences · 2022
    Article
  7. Review
  8. Review
  9. Frontiers in immunology · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuta YoshinoDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Yuki OzakiDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Kiyohiro YamazakiDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Tomoko SaoDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Yoko MoriDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Shinichiro OchiDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Jun-Ichi IgaDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.
Shu-Ichi UenoDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of MedicineToon, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A hypothesis for schizophrenia (SCZ) called the "microglia hypothesis" has been suggested. In SCZ, expression of

Indexed as

methylation ratemRNA expressionpyrosequencingschizophreniasusceptibility markerTREM2triggering receptor expressed on myeloid cell 2

Identifiers

PMID28588439
PMCPMC5440575

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.