ArticleThrombosis journal2017
Effects of Ramadan fasting on platelet reactivity in diabetic patients treated with clopidogrel.
Article in Thrombosis journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02720133 (Ramadan Fasting Effects in Patients With Cardiovascular Risk Factors), which is not on this map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ramadan Fasting Effects in Patients With Cardiovascular Risk Factors
Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Expression of Concern: Effects of Ramadan fasting on aspirin resistance in type 2 diabetic patients.PloS one · 2026Article
- A multicenter mixed-methods study on the effects of intermittent fasting in patients with immune thrombocytopenia receiving thrombopoietin receptor agonists.Frontiers in nutrition · 2025Article
- The impact of Ramadan intermittent fasting on anthropometric measurements and body composition: Evidence from LORANS study and a meta-analysis.Frontiers in nutrition · 2023Review
- The safety of Ramadan Fasting following Percutaneous Coronary Intervention.BMC cardiovascular disorders · 2020Article
- Ramadan and Diabetes: A Narrative Review and Practice Update.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020Review
- Ramadan and Diabetes: A Narrative Review and Practice Update.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020Review
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effects of Ramadan fasting (RF) on clopidogrel antiplatelet inhibition were not previously investigated. The present study evaluated the influence of RF on platelet reactivity in patients with high cardiovascular risk (CVR) in particular those with type 2 diabetes mellitus (DM).
methodsA total of 98 stable patients with ≥2 CVR factors were recruited. All patients observed RF and were taking clopidogrel at a maintenance dose of 75 mg. Clinical findings and serum lipids data were recorded before Ramadan (Pre-R), at the last week of Ramadan (R) and 4 weeks after the end of Ramadan (Post-R). During each patient visit, nutrients intakes were calculated and platelet reactivity assessment using Verify Now P2Y12 assay was performed.
resultsIn DM patients, the absolute PRU changes from baseline were +27 (
conclusionsRF significantly decreased platelet sensitivity to clopidogrel in DM patients during and after Ramadan. This effect is possibly related to an increase of glycemia and serum lipids levels induced by fasting.
trial registrationClinical Trials.gov NCT02720133. Registered 24 July 2014.Retrospectively registered.
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Registered trials
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