ArticleScientific reports2017
Fused Deposition Modeling (FDM) 3D Printed Tablets for Intragastric Floating Delivery of Domperidone.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 281 citations in OpenAlex.
- Three-Dimensional Printing for Precision and Personalized Patient Care: A New Paradigm for Pharmacy Practice?Pharmaceutics · 2026Review
- Fabrication of Gastroretentive and Extended-Release Famotidine Floating Tablets via Fused Deposition Modeling.AAPS PharmSciTech · 2025Article
- Therapeutic Precision: Unveiling the Potential of 3D Printing in Drug Delivery, Tissue Engineering, and Regenerative Medicine.3D printing and additive manufacturing · 2025Article
- Formulation and Structural Optimisation of PVA-Fibre Biopolymer Composites for 3D Printing in Drug Delivery Applications.Polymers · 2025Article
- Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations.Molecules (Basel, Switzerland) · 2025Review
- The Future of Medicine: How 3D Printing Is Transforming Pharmaceuticals.Pharmaceutics · 2025Review
- Utilizing Food Waste in 3D-Printed PLA Formulations to Achieve Sustainable and Customizable Controlled Delivery Systems.ACS omega · 2024Article
- Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters.Pharmaceutics · 2024Article
- Fabrication of 3D-Printed Hydrocortisone Triple Pulsatile Tablet Using Fused Deposition Modelling Technology.AAPS PharmSciTech · 2024Article
- Bibliometric Analysis-Based Review of Fused Deposition Modeling 3D Printing Method (1994-2020).3D printing and additive manufacturing · 2024Review
- Status of Polymer Fused Deposition Modeling (FDM)-Based Three-Dimensional Printing (3DP) in the Pharmaceutical Industry.Polymers · 2024Review
- Fixed-Dose Combination Formulations in Solid Oral Drug Therapy: Advantages, Limitations, and Design Features.Pharmaceutics · 2024Review
- Potential Applications and Additive Manufacturing Technology-Based Considerations of Mesoporous Silica: A Review.AAPS PharmSciTech · 2023Review
- Additive manufacturing technologies with emphasis on stereolithography 3D printing in pharmaceutical and medical applications: A review.International journal of pharmaceutics: X · 2023Article
- 3D Printing of Personalised Carvedilol Tablets Using Selective Laser Sintering.Pharmaceutics · 2023Article
- Fused Deposition Modelling 3D-Printed Gastro-Retentive Floating Device for Propranolol Hcl Tablets.Polymers · 2023Article
- Recent developments in natural biopolymer based drug delivery systems.RSC advances · 2023Review
- Design and Development of Sublingual Printlets Containing Domperidone Nanocrystals Using 3D Melting Solidification Printing Process (MESO-PP).Pharmaceutics · 2023Article
- Hydrophilic High Drug-Loaded 3D Printed Gastroretentive System with Robust Release Kinetics.Pharmaceutics · 2023Article
- Dose Titration of Solid Dosage Forms via FDM 3D-Printed Mini-Tablets.Pharmaceutics · 2022Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to explore the feasibility of fused deposition modeling (FDM) 3D printing to prepare intragastric floating sustained release (FSR) tablets. Domperidone (DOM), an insoluble weak base, was chosen as a model drug to investigate the potential of FSR in increasing its oral bioavailability and reducing its administration frequency. DOM was successfully loaded into hydroxypropyl cellulose (HPC) filaments using hot melt extrusion (HME). The filaments were then printed into hollow structured tablets through changing the shell numbers and the infill percentages. Physical characterization results indicated that the majority of DOM gradually turned into the amorphous form during the fabrication process. The optimized formulation (contain 10% DOM, with 2 shells and 0% infill) exhibited the sustained release characteristic and was able to float for about 10 h in vitro. Radiographic images showed that the BaSO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.