Evidence map›Paper›PMID 28588092›Full record

ArticleJournal of the American Heart Association2017

Stunning and Right Ventricular Dysfunction Is Induced by Coronary Balloon Occlusion and Rapid Pacing in Humans: Insights From Right Ventricular Conductance Catheter Studies.

Richard G Axell, Joel P Giblett, Paul A White, Andrew Klein, James Hampton-Til, Michael O'Sullivan, Denise Braganza, William R Davies, Nick E J West, Cameron G Densem and 1 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Richard G AxellMedical Physics and Clinical Engineering, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Joel P GiblettDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
Paul A WhiteMedical Physics and Clinical Engineering, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Andrew KleinDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
James Hampton-TilPostgraduate Medical Institute, Anglia Ruskin University, Chelmsford, United Kingdom.
Michael O'SullivanDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
Denise BraganzaDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
William R DaviesDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
Nick E J WestDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
Cameron G DensemDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom.
Stephen P HooleDepartment of Interventional Cardiology, Papworth Hospital, Cambridge, United Kingdom s.hoole@nhs.net.
Papworth Hospital · GBAnglia Ruskin University · GBCambridge University Hospitals NHS Foundation Trust · GB

Funding

Department of Health NIHR-HCS-D12-03-14
6 · The paper itself

Abstract

backgroundWe sought to determine whether right ventricular stunning could be detected after supply (during coronary balloon occlusion [BO]) and supply/demand ischemia (induced by rapid pacing [RP] during transcatheter aortic valve replacement) in humans. METHODS AND

resultsTen subjects with single-vessel right coronary artery disease undergoing percutaneous coronary intervention with normal ventricular function were studied in the BO group. Ten subjects undergoing transfemoral transcatheter aortic valve replacement were studied in the RP group. In both, a conductance catheter was placed into the right ventricle, and pressure volume loops were recorded at baseline and for intervals over 15 minutes after a low-pressure BO for 1 minute or a cumulative duration of RP for up to 1 minute. Ischemia-induced diastolic dysfunction was seen 1 minute after RP (end-diastolic pressure [mm Hg]: 8.1±4.2 versus 12.1±4.1,

conclusionsRP and right coronary artery balloon occlusion both cause ischemic right ventricular dysfunction with stunning observed later during the procedure. This may have intraoperative implications in patients without right ventricular functional reserve.

Indexed as

Ventricular Function, RightAgedAged, 80 and overAortic Valve StenosisBalloon OcclusionCardiac CatheterizationCardiac Pacing, ArtificialCoronary Artery DiseaseFemaleHumansMaleMyocardial StunningPercutaneous Coronary InterventionRecovery of FunctionRisk FactorsStroke Volumemyocardialpercutaneous coronary interventionrapid pacingright ventricular dysfunctionstunningtranscatheter aortic valve implantation

Identifiers

PMID28588092
PMCPMC5669185
OpenAlexW2621945301

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.