Evidence map›Paper›PMID 28588035›Full record

ArticleGenetics2017

Control of a Novel Spermatocyte-Promoting Factor by the Male Germline Sex Determination Factor PHF7 of

Shu Yuan Yang, Yi-Chieh Chang, Yu Hsin Wan, Cale Whitworth, Ellen M Baxter, Shekerah Primus, Haiwei Pi, Mark Van Doren

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Direct reprogramming as a route to cardiac repair.Seminars in cell & developmental biology · 2022
    Review
  5. A conserved role ofPeerJ · 2022
    Article
  6. Article
  7. Article
  8. An autoregulatory switch in sex-specificDevelopment (Cambridge, England) · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Shu Yuan YangDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan yangsy@mail.cgu.edu.tw vandoren@jhu.edu.ORCID 0000-0002-4709-6551
Yi-Chieh ChangGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Yu Hsin WanDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Cale WhitworthDepartment of Biology, Johns Hopkins University, Baltimore, Maryland 21218.
Ellen M BaxterDepartment of Biology, Johns Hopkins University, Baltimore, Maryland 21218.
Shekerah PrimusDepartment of Biology, Johns Hopkins University, Baltimore, Maryland 21218.
Haiwei PiDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Mark Van DorenDepartment of Biology, Johns Hopkins University, Baltimore, Maryland 21218 yangsy@mail.cgu.edu.tw vandoren@jhu.edu.
Johns Hopkins University · USChang Gung University · TWChang Gung Memorial Hospital · TW

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Sexual development of the Drosophila gonadR01GM084356 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 2009 to 2016
$2.9M
NIGMS NIH HHS R01 GM084356NIGMS NIH HHS T32 GM007231NIH HHS P40 OD018537
6 · The paper itself

Abstract

A key aspect of germ cell development is to establish germline sexual identity and initiate a sex-specific developmental program to promote spermatogenesis or oogenesis. Previously, we have identified the histone reader Plant Homeodomain Finger 7 (PHF7) as an important regulator of male germline identity. To understand how PHF7 directs sexual differentiation of the male germline, we investigated the downstream targets of PHF7 by combining transcriptome analyses, which reveal genes regulated by

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsHistonesHomeodomain ProteinsMaleSpermatocytesSpermatogenesisDrosophila ProteinsHistonesHomeodomain ProteinsPHF7 protein, DrosophilaREEPL1 protein, DrosophilaGenetics of Sexgermline sex determinationPhf7REEP familyspermatogenesis

Identifiers

PMID28588035
PMCPMC5560799
OpenAlexW2624403653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.