Evidence map›Paper›PMID 28588016›Full record

ArticleThe Journal of experimental medicine2017

Commensal microbes provide first line defense against

Simone Becattini, Eric R Littmann, Rebecca A Carter, Sohn G Kim, Sejal M Morjaria, Lilan Ling, Yangtsho Gyaltshen, Emily Fontana, Ying Taur, Ingrid M Leiner and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 223 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Impact of the defined Oligo-MMScientific reports · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. ComparingGut microbes · 2025
    Article
  12. Listeriosis.Nature reviews. Disease primers · 2025
    Review
  13. Microorganisms · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Whole Genome Analysis ofAntibiotics (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Article
  20. Comparative Analysis ofMicroorganisms · 2025
    Article

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Simone BecattiniImmunology Program, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY becattis@mskcc.org pamere@mskcc.org.ORCID http://orcid.org/0000-0001-5985-0403
Eric R LittmannLucille Castori Center for Microbes Inflammation and Cancer, Molecular Microbiology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY.
Rebecca A CarterImmunology Program, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY.ORCID http://orcid.org/0000-0001-9967-2955
Sohn G KimImmunology Program, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY.
Sejal M MorjariaInfectious Diseases Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY.
Lilan LingLucille Castori Center for Microbes Inflammation and Cancer, Molecular Microbiology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY.
Yangtsho GyaltshenLucille Castori Center for Microbes Inflammation and Cancer, Molecular Microbiology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY.
Emily FontanaLucille Castori Center for Microbes Inflammation and Cancer, Molecular Microbiology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY.ORCID http://orcid.org/0000-0002-9060-5382
Ying TaurLucille Castori Center for Microbes Inflammation and Cancer, Molecular Microbiology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY.
Ingrid M LeinerImmunology Program, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY.
Eric G PamerImmunology Program, Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY becattis@mskcc.org pamere@mskcc.org.ORCID http://orcid.org/0000-0002-6755-9904
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Systems Biology of Microbiome-mediated Resilience to Antibiotic-resistant PathogensU01AI124275 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI PAMER, ERIC G., XAVIER, JOAO · 2016 to 2020
$8.9M
TNF Mediated Immune Defense Against Listeria InfectionR01AI042135 · NIAID · YALE UNIVERSITY · PI PAMER, ERIC G. · 1998 to 2019
$7.3M
Effects of the Intestinal Microbiota on Infections During Bone Marrow TransplantK23AI095398 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI TAUR, YING · 2011 to 2015
$651k
NCI NIH HHS P30 CA008748NIAID NIH HHS K23 AI095398NIAID NIH HHS R01 AI042135NIAID NIH HHS U01 AI124275
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsAntibiosisFecesGastrointestinal MicrobiomeHost-Pathogen InteractionsHumansImmunocompromised HostIntestinesListeria monocytogenesListeriosisMice, Inbred C57BLMice, KnockoutSurvival AnalysisSurvival RateTime FactorsAnti-Bacterial Agents

Identifiers

PMID28588016
PMCPMC5502438
OpenAlexW2624595700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.