Evidence map›Paper›PMID 28587814›Full record

ArticleSchizophrenia research2018

Motion energy analysis reveals altered body movement in youth at risk for psychosis.

Derek J Dean, Alayna T Samson, Raeana Newberry, Vijay A Mittal

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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  10. Prediction, Psychosis, and the Cerebellum.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Derek J DeanUniversity of Colorado Boulder, Department of Psychology and Neuroscience, Boulder, CO, USA; University of Colorado Boulder, Center for Neuroscience, Boulder, CO, USA. Electronic address: derek.dean@colorado.edu.
Alayna T SamsonChildren's Hospital Colorado, Denver, CO, USA.
Raeana NewberryUniversity of Colorado Boulder, Department of Psychology and Neuroscience, Boulder, CO, USA.
Vijay A MittalNorthwestern University, Department of Psychology, Evanston, IL, USA; Northwestern University, Department of Psychiatry, Chicago, IL, USA; Northwestern University, Institute for Policy Research, Evanston, IL, USA; Northwestern University, Medical Social Sciences, Chicago, IL, USA.
University of Colorado Boulder · USChildren's Hospital Colorado · USNorthwestern University · US

Funding

Frontal-Subcortical Development, Movement Abnormalities, and Risk for PsychosisR01MH094650 · NIMH · UNIVERSITY OF COLORADO · PI MITTAL, VIJAY A · 2011 to 2015
$2.3M
Exercise and markers of medial temporal health in youth at-risk for psychosisR33MH103231 · NIMH · NORTHWESTERN UNIVERSITY · PI BRYAN, ANGELA, MITTAL, VIJAY A · 2016 to 2018
$689k
Exercise and markers of medial temporal health in youth at-risk for psychosisR21MH103231 · NIMH · UNIVERSITY OF COLORADO · PI BRYAN, ANGELA, MITTAL, VIJAY A · 2014 to 2015
$489k
NIMH NIH HHS R01 MH094650NIMH NIH HHS R21 MH103231NIMH NIH HHS R33 MH103231
6 · The paper itself

Abstract

backgroundGrowing evidence suggests that movement abnormalities occur prior to the onset of psychosis. Innovations in technology and software provide the opportunity for a fine-tuned and sensitive measurement of observable behavior that may be particularly useful to detecting the subtle movement aberrations present during the prodromal period.

methodsIn the present study, 54 youth at ultrahigh risk (UHR) for psychosis and 62 healthy controls participated in structured clinical interviews to assess for an UHR syndrome. The initial 15min of the baseline clinical interview was assessed using Motion Energy Analysis (MEA) providing frame-by-frame measures of total movement, amplitude, speed, and variability of both head and body movement separately.

resultsResult showed region-specific group differences such that there were no differences in head movement but significant differences in body movement. Specifically, the UHR group showed greater total body movement and speed of body movements, and lower variation in body movement compared to healthy controls. However, there were no significant associations with positive, negative or disorganized symptom domains.

conclusionThis study represents an innovative perspective on gross motor function in the UHR group. Importantly, the automated approach used in this study provides a sensitive and objective measure of body movement abnormalities, potentially guiding novel assessment and prevention of symptom development in those at risk for psychosis.

Indexed as

MovementAdolescentBiomechanical PhenomenaChildFemaleHumansInterview, PsychologicalMaleProdromal SymptomsPsychotic DisordersRiskYoung AdultGross motorMotion energy analysisMovement abnormalitiesPsychosisUltrahigh risk

Identifiers

PMID28587814
PMCPMC5712481
OpenAlexW2621225995

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.