Evidence map›Paper›PMID 28587807›Full record

ArticleNeurotoxicology2018

Association of MRI T1 relaxation time with neuropsychological test performance in manganese- exposed welders.

R M Bowler, C-L Yeh, S W Adams, E J Ward, R E Ma, S Dharmadhikari, S A Snyder, S E Zauber, C W Wright, U Dydak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotoxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

R M BowlerSan Francisco State University, Department of Psychology, 1600 Holloway Ave., San Francisco, CA 94132, USA. Electronic address: rbowl@sfsu.edu.
C-L YehSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907, USA; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 950 W. Walnut Street, Indianapolis, IN, 46202, USA.
S W AdamsSan Francisco State University, Department of Psychology, 1600 Holloway Ave., San Francisco, CA 94132, USA.
E J WardSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907, USA.
R E MaSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907, USA; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 950 W. Walnut Street, Indianapolis, IN, 46202, USA.
S DharmadhikariDepartment of Radiology and Imaging Sciences, Emory University Hospital,1364 Clifton Road, Atlanta, GA, 30322, USA.
S A SnyderSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907, USA; Department of Speech, Language and Hearing Sciences, Purdue University, 715 Clinic Drive, West Lafayette, IN 47907, USA.
S E ZauberDepartment of Neurology, Indiana University School of Medicine, 355 W 16th St, Indianapolis, IN 46202, USA.
C W WrightSan Francisco State University, Department of Psychology, 1600 Holloway Ave., San Francisco, CA 94132, USA.
U DydakSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907, USA; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 950 W. Walnut Street, Indianapolis, IN, 46202, USA; Department of Speech, Language and Hearing Sciences, Purdue University, 715 Clinic Drive, West Lafayette, IN 47907, USA. Electronic address: udydak@purdue.edu.

Funding

Neuroimaging for Early Diagnosis of Manganese Toxicity in Humans and RodentsR01ES020529 · NIEHS · PURDUE UNIVERSITY · PI DYDAK, ULRIKE · 2011 to 2015
$2.0M
Occupational Safety and Health Training GrantT03OH008615 · OH · PURDUE UNIVERSITY · PI WELLS, ELLEN M · 2011 to 2025
$1.7M
ACL HHS T03OH008615NIEHS NIH HHS R01 ES020529NIOSH CDC HHS T03 OH008615
6 · The paper itself

Abstract

This study examines the results of neuropsychological testing of 26 active welders and 17 similar controls and their relationship to welders' shortened MRI T1 relaxation time, indicative of increased brain manganese (Mn) accumulation. Welders were exposed to Mn for an average duration of 12.25 years to average levels of Mn in air of 0.11±0.05mg/m

Indexed as

Occupational ExposureWeldingAdultBrainHumansMagnetic Resonance ImagingMaleManganese PoisoningMiddle AgedNeuropsychological Tests

Identifiers

PMID28587807
PMCPMC5905426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.