Trial reportInternational journal of neural systems2017
Surface EEG-Transcranial Direct Current Stimulation (tDCS) Closed-Loop System.
Trial report in International journal of neural systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transcranial direct current stimulation for gait recovery following stroke: A systematic review of current literature and beyond.Frontiers in neurology · 2022Pooled it
- Practice improves older adults' attentional control and prospective memory more than HD-tDCS: a randomized controlled trial.Scientific reports · 2024Trial
- Personalized cognitive enhancement for older adults: An aging-friendly closed-loop human-machine interface framework.Ageing research reviews · 2025Review
- Manipulation of neuronal activity by an artificial spiking neural network implemented on a closed-loop brain-computer interface in non-human primates.Journal of neural engineering · 2025Article
- An Anticipatory Approach to Ethico-Legal Implications of Future Neurotechnology.Science and engineering ethics · 2024Article
- Closed-Loop Transcranial Electrical Neurostimulation for Sustained Attention Enhancement: A Pilot Study towards Personalized Intervention Strategies.Bioengineering (Basel, Switzerland) · 2024Article
- Cellular mechanisms underlying carry-over effects after magnetic stimulation.Scientific reports · 2024Article
- Transcranial Direct Current Stimulation Decreases P3 Amplitude and Inherent Delta Activity during a Waiting Impulsivity Paradigm: Crossover Study.Brain sciences · 2024Article
- The use of noninvasive brain stimulation techniques in autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2024Article
- Article
- Closing the loop between brain and electrical stimulation: towards precision neuromodulation treatments.Translational psychiatry · 2023Review
- Brain stimulation treatment for bipolar disorder.Bipolar disorders · 2023Review
- Favoring the cognitive-motor process in the closed-loop of BCI mediated post stroke motor function recovery: challenges and approaches.Frontiers in neurorobotics · 2023Review
- Neuron matters: neuromodulation with electromagnetic stimulation must consider neurons as dynamic identities.Journal of neuroengineering and rehabilitation · 2022Review
- Deep brain-machine interfaces: sensing and modulating the human deep brain.National science review · 2022Review
- Electroencephalographic Patterns in taVNS: A Systematic Review.Biomedicines · 2022Review
- Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation.Scientific reports · 2022Article
- Mathematical Model Insights into EEG Origin under Transcranial Direct Current Stimulation (tDCS) in the Context of Psychosis.Journal of clinical medicine · 2022Article
- Transcranial Electrical Stimulation for Psychiatric Disorders in Adults: A Primer.Focus (American Psychiatric Publishing) · 2022Review
- Speed of Processing (SoP) Training Plus α-tACS in People With Mild Cognitive Impairment: A Double Blind, Parallel, Placebo Controlled Trial Study Protocol.Frontiers in aging neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Conventional transcranial direct current stimulation (tDCS) protocols rely on applying electrical current at a fixed intensity and duration without using surrogate markers to direct the interventions. This has led to some mixed results; especially because tDCS induced effects may vary depending on the ongoing level of brain activity. Therefore, the objective of this preliminary study was to assess the feasibility of an EEG-triggered tDCS system based on EEG online analysis of its frequency bands. Six healthy volunteers were randomized to participate in a double-blind sham-controlled crossover design to receive a single session of 10[Formula: see text]min 2[Formula: see text]mA cathodal and sham tDCS. tDCS trigger controller was based upon an algorithm designed to detect an increase in the relative beta power of more than 200%, accompanied by a decrease of 50% or more in the relative alpha power, based on baseline EEG recordings. EEG-tDCS closed-loop-system was able to detect the predefined EEG magnitude deviation and successfully triggered the stimulation in all participants. This preliminary study represents a proof-of-concept for the development of an EEG-tDCS closed-loop system in humans. We discuss and review here different methods of closed loop system that can be considered and potential clinical applications of such system.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.