Evidence map›Paper›PMID 28587375›Full record

ArticleExperimental and therapeutic medicine2017

C-X-C motif chemokine ligand 8 promotes endothelial cell homing via the Akt-signal transducer and activator of transcription pathway to accelerate healing of ischemic and hypoxic skin ulcers.

Lei Shen, Peng Zhang, Shanqiang Zhang, Liping Xie, Lijie Yao, Weiya Lang, Jie Lian, Wei Qin, Meng Zhang, Liang Ji

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lei ShenDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Peng ZhangDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Shanqiang ZhangDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Liping XieDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Lijie YaoDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Weiya LangDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Jie LianDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Wei QinDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Meng ZhangDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Liang JiDepartment of Anatomy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Qiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C motif chemokine ligand 8 (CXCL-8) promotes cell homing and angiogenesis. However, under hypoxic conditions, the role of CXCL-8 in the homing of human umbilical vein endothelial cells (HUVECs), and its effect on the healing of skin ulcers caused by ischemia and hypoxia remain unknown. In the current study, assays measuring cell proliferation,

Indexed as

cell homingC-X-C motif chemokine ligand 8human umbilical vein endothelial cellshypoxiaskin ulcer

Identifiers

PMID28587375
PMCPMC5450563
OpenAlexW2604528893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.