Evidence map›Paper›PMID 28587374›Full record

ArticleExperimental and therapeutic medicine2017

Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1β-stimulated human chondrocytes.

Nan Yao, Neng Chen, Xuemeng Xu, Dongmei Sun, Wengang Liu, Gang Li, Xiaoli Bi, Sumei Li, Zhao Chen, Guocai Chen and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Shaoyangzhugu Formula regulates p19Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nan YaoOrthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510095, P.R. China.
Neng ChenOrthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510095, P.R. China.
Xuemeng XuOrthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510095, P.R. China.
Dongmei SunGuangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong 510095, P.R. China.
Wengang LiuOrthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510095, P.R. China.
Gang LiAcademic Affairs Office, Guangdong Food and Drug Vocational College, Guangzhou, Guangdong 510520, P.R. China.
Xiaoli BiGuangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong 510095, P.R. China.
Sumei LiGuangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong 510095, P.R. China.
Zhao ChenGuangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong 510095, P.R. China.
Guocai ChenOrthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510095, P.R. China.
Haining GanGuangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong 510095, P.R. China.
Guangdong Provincial Hospital of Traditional Chinese Medicine · CNGuangdong Food and Drug Vocational College · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shenmai injection (SMI) has been widely used as a therapy to treat a number of diseases. However, its anti-osteoarthritic properties have not yet been fully investigated. In the present study, the protective effect of SMI on knee articular cartilage of anterior cruciate ligament transected rabbits and interleukin-1β (IL-1β)-stimulated human chondrocytes was investigated. For the

Indexed as

anterior cruciate ligament transectioncartilagechondrocytesknee osteoarthritisShenmai injection

Identifiers

PMID28587374
PMCPMC5450727
OpenAlexW2606486588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.