Evidence map›Paper›PMID 28587284›Full record

ReviewSensors (Basel, Switzerland)2017

Bioluminescence Assays for Monitoring Chondrogenic Differentiation and Cartilage Regeneration.

Hyeon Jeong Je, Min Gu Kim, Hyuck Joon Kwon

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hyeon Jeong JeDepartment of Physical Therapy and Rehabilitation Science, College of Health Science, Eulji University, Gyeonggi 13135, Korea. runbee38@hanmail.net.
Min Gu KimDepartment of Physical Therapy and Rehabilitation Science, College of Health Science, Eulji University, Gyeonggi 13135, Korea. kevinzoq@naver.com.
Hyuck Joon KwonDepartment of Physical Therapy and Rehabilitation Science, College of Health Science, Eulji University, Gyeonggi 13135, Korea. kwonhj@eulji.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since articular cartilage has a limited regeneration potential, for developing biological therapies for cartilage regeneration it is important to study the mechanisms underlying chondrogenesis of stem cells. Bioluminescence assays can visualize a wide range of biological phenomena such as gene expression, signaling, metabolism, development, cellular movements, and molecular interactions by using visible light and thus contribute substantially to elucidation of their biological functions. This article gives a concise review to introduce basic principles of bioluminescence assays and applications of the technology to visualize the processes of chondrogenesis and cartilage regeneration. Applications of bioluminescence assays have been highlighted in the methods of real-time monitoring of gene expression and intracellular levels of biomolecules and noninvasive cell tracking within animal models. This review suggests that bioluminescence assays can be applied towards a visual understanding of chondrogenesis and cartilage regeneration.

Indexed as

ChondrogenesisAnimalsCartilage, ArticularCell DifferentiationChondrocytesHumansMesenchymal Stem CellsRegenerationStem Cellsbioluminescence assayscartilage regenerationchondrogenesisin vivo bioluminescence imagingreal-time monitoring

Identifiers

PMID28587284
PMCPMC5492100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.