Evidence map›Paper›PMID 28587282›Full record

ArticleNutrients2017

Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage.

Claudia Loganes, Sara Lega, Matteo Bramuzzo, Liza Vecchi Brumatti, Elisa Piscianz, Erica Valencic, Alberto Tommasini, Annalisa Marcuzzi

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  8. RNA-seq andJournal of immunology research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Claudia LoganesDepartment of Paediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, Trieste 34137, Italy. claudia.loganes@gmail.com.
Sara LegaDepartment of Medicine, Surgery, and Health Sciences, University of Trieste, Strada di Fiume, 447, Trieste 34100, Italy. saralega83@gmail.com.
Matteo BramuzzoDepartment of Paediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, Trieste 34137, Italy. matteo.bramuzzo@burlo.trieste.it.
Liza Vecchi BrumattiDepartment of Paediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, Trieste 34137, Italy. liza.vecchibrumatti@burlo.trieste.it.
Elisa PiscianzDepartment of Medicine, Surgery, and Health Sciences, University of Trieste, Strada di Fiume, 447, Trieste 34100, Italy. elisa.piscianz@burlo.trieste.it.
Erica ValencicDepartment of Paediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, Trieste 34137, Italy. erica.valencic@burlo.trieste.it.
Alberto TommasiniDepartment of Paediatrics, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, Trieste 34137, Italy. alberto.tommasini@burlo.trieste.it.
Annalisa MarcuzziDepartment of Medicine, Surgery, and Health Sciences, University of Trieste, Strada di Fiume, 447, Trieste 34100, Italy. annalisa.marcuzzi@burlo.trieste.it.
IRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to determine if a preventive treatment with curcumin can protect intestinal epithelial cells from inflammatory damage induced by IFNγ. To achieve this goal we have used a human intestinal epithelial cell line (HT29) treated with IFNγ to undergo apoptotic changes that can reproduce the damage of intestinal epithelia exposed to inflammatory cytokines. In this model, we measured the effect of curcumin (curcuminoid from

Indexed as

Anti-Inflammatory Agents, Non-SteroidalApoptosisCell SurvivalCurcumaCurcuminCytokinesEpithelial CellsHT29 CellsHumansInflammationInterferon-gammaInterleukin-7Intestinal MucosaNF-kappa BPhosphorylationSignal TransductionAnti-Inflammatory Agents, Non-SteroidalCurcuminCytokinesInterferon-gammaInterleukin-7NF-kappa Bapoptosiscurcumincytokinesepithelial cell lineintestinal inflammation

Identifiers

PMID28587282
PMCPMC5490557
OpenAlexW2623930213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.