Evidence map›Paper›PMID 28587261›Full record

ArticleInternational journal of molecular sciences2017

Ulmus macrocarpa Hance Extracts Attenuated H₂O₂ and UVB-Induced Skin Photo-Aging by Activating Antioxidant Enzymes and Inhibiting MAPK Pathways.

Sun-Il Choi, Jin-Ha Lee, Jae-Min Kim, Tae-Dong Jung, Bong-Yeon Cho, Seung-Hyun Choi, Dae-Won Lee, Jinkyung Kim, Jong-Yea Kim, Ok-Hawn Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Food science and biotechnology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Antioxidative Role ofAntioxidants (Basel, Switzerland) · 2022
    Article
  10. SCAInternational journal of molecular sciences · 2022
    Article
  11. Flavonoid Glycosides fromACS omega · 2022
    Article
  12. Potential lipid-lowering effects ofFrontiers in medicine · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sun-Il ChoiDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. docgotack89@hanmail.net.
Jin-Ha LeeDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. tre98@hanmail.net.
Jae-Min KimDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. akxlwmf@nate.com.
Tae-Dong JungDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. lgtjtd@naver.com.
Bong-Yeon ChoDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. bongyeon.cho92@gmail.com.
Seung-Hyun ChoiDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. zzaoszz@naver.com.
Dae-Won LeeJeongseon Yaccho Co., Ltd., Jeongseon 26125, Korea. doll3261@naver.com.
Jinkyung KimJeongseon Yaccho Co., Ltd., Jeongseon 26125, Korea. mintcandy802@hanmail.net.
Jong-Yea KimDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. jongkim@kangwon.ac.kr.
Ok-Hawn LeeDepartment of Food Science and Biotechnology, Kangwon National University, Chuncheon 24341, Korea. loh99@kangwon.ac.kr.
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To protect from reactive oxygen species (ROS) damages, skin cells have evolved to have antioxidant enzymes, such as copper and zinc-dependent superoxide dismutase (SOD1), mitochondrial manganese-dependent superoxide dismutase (SOD2), catalase (CAT), glutathione peroxidase (GPX), and glutathione reductase (GR), and suppressed the expression of matrix metalloproteinases (MMPs) through the mitogen-activated protein kinase (MAPK) signaling pathways, such as c-Jun N-terminal kinase (JNK) and p38. Bioactive compounds analyses were performed using a high-performance liquid chromatography-photodiode array detector (HPLC-PDA) system. The antioxidant activity of

Indexed as

AnimalsAntioxidantsCatalaseCell DeathEnzyme ActivatorsFibroblastsGene Expression Regulation, EnzymologicGlutathione PeroxidaseHumansHydrogen PeroxideMaleMAP Kinase Signaling SystemMicePlant ExtractsReactive Oxygen SpeciesSkinAntioxidantsCatalaseEnzyme ActivatorsGlutathione PeroxidaseHydrogen PeroxidePlant ExtractsReactive Oxygen SpeciesSuperoxide DismutaseSuperoxide Dismutase 2anti-agingantioxidanthairless micehuman dermal fibroblastsUlmus macrocarpa Hance extracts

Identifiers

PMID28587261
PMCPMC5486023
OpenAlexW2624319814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.