Evidence map›Paper›PMID 28587146›Full record

ArticleInternational journal of environmental research and public health2017

Evaluation of the Dietary Intake of Cadmium, Lead and Mercury and Its Relationship with Bone Health among Postmenopausal Women in Spain.

Luis M Puerto-Parejo, Ignacio Aliaga, María L Canal-Macias, Olga Leal-Hernandez, Raul Roncero-Martín, Sergio Rico-Martín, Jose M Moran

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Exposure to heavy metals and the risk of osteopenia or osteoporosis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  2. Review
  3. Article
  4. Screening of bioactive components inToxicology reports · 2025
    Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Protective effect of tea against lead and cadmium-induced oxidative stress-a review.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2018
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Luis M Puerto-ParejoMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. lmpuerto@unex.es.
Ignacio AliagaMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. i.aliaga@pdi.ucm.es.
María L Canal-MaciasMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. luzcanal@unex.es.
Olga Leal-HernandezMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. olgaleal@unex.es.
Raul Roncero-MartínMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. rronmar@unex.es.
Sergio Rico-MartínMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. sergiorico@unex.es.
Jose M MoranMetabolic Bone Diseases Research Group, Nursing Department, University of Extremadura, 10003 Caceres, Spain. jmmorang@unex.es.
Universidad de Extremadura · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeavy metals, such as lead, cadmium, and mercury, are absorbed through contaminated food sources and water. Few studies have investigated the extent to which dietary heavy metals are associated with low bone mineral density.

aimsWe aimed to characterize the dietary intake of the heavy metals lead, cadmium and mercury among healthy, non-smoking postmenopausal women in Spain. Furthermore, we sought to establish a putative relationship between bone health and the intake of these heavy metals in this population. STUDY

designThe daily intake of the heavy metals considered for the different food groups was calculated by accounting for food content and consumption in 281 postmenopausal women. Bone measurements were performed using a Quantitative Bone Ultrasound (QUS), a Dual-Energy X-ray Absorptiometry (DXA) and a Peripheral Quantitative Computed Tomography (pQCT).

resultsThe average estimated dietary cadmium exposure among the 281 women studied was 29.87 μg/day (20.41-41.04) and 3.03 μg/kg body weight (b.w.; 2.17-4.40). Dietary lead exposure was 46.24 μg/day (38.11-54.77) and 4.87 μg/kg b.w. (4.00-6.14). The estimated dietary mercury exposure was 11.64 μg/day and 1.19 μg/kg b.w. (0.82-1.76). Participants were classified according to their heavy metal intake (above or below the respective medians). After further adjustment for potential confounding factors, no significant differences were found in all the measured parameters (

conclusionsWe did not find associations between bone health and the dietary intake of three heavy metals in postmenopausal women. Dietary intake of the measured heavy metals were within the recommended values.

Indexed as

Bone DensityDietAbsorptiometry, PhotonCadmiumEnvironmental PollutantsFemaleHumansLeadMercuryMiddle AgedPostmenopauseSpainCadmiumEnvironmental PollutantsLeadMercurydiet recordsdual X-ray absorptiometryheavy metalsquantitative bone ultrasoundtomography

Identifiers

PMID28587146
PMCPMC5486250
OpenAlexW2617390012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.