Evidence map›Paper›PMID 28587143›Full record

ReviewCancers2017

Improving Outcomes in Patients with CRC: The Role of Patient Reported Outcomes-An ESDO Report.

Eric Van Cutsem, Aimery De Gramont, Geoffrey Henning, Philippe Rougier, Franck Bonnetain, Thomas Seufferlein

Registry-linked trialAbstract readReview
In one paragraph

Review in Cancers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03965325 (FOcUs on Colorectal CAncer oUtcomes), which is not on this map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03965325 completednot on this mapstarted 2019, after this paper: background citation

FOcUs on Colorectal CAncer oUtcomes: Long-Term Study

TypeobservationalSponsorIHU StrasbourgRan2019 to 2024Enrolled133ConditionsColorectal CancerArmsUse of a standardized set to collect clinical and patient-centered data, to assess the trend of the Global Health Status overtime in colorectal cancer patients
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. MiR-92a promotes the invasion and migration of colorectal cancer by targeting RECK.International journal of clinical and experimental pathology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric Van CutsemDepartment of Digestive Oncology, University Hospitals Gasthuisberg, and KU Leuven, 493000 Leuven, Belgium. eric.vancutsem@kuleuven.be.
Aimery De GramontService d'Oncologie Médicale/Oncology Department, Institut hospitalier Franco-Britannique/Franco-British Institute, 92300 Levallois-Perret, France. aimerydegramont@gmail.com.
Geoffrey HenningEuropaColon, London N16 8ST, UK. geoffrey@europacolon.com.
Philippe RougierHepato-Gastroenterology and Digestive Oncology Department, University Hospital Hotel Dieu, IMAD, 44000 Nantes, France. rougier.philippe2012@gmail.com.
Franck BonnetainMethodology and Quality of Life Department, University Hospital of Besançon & INSERM 1098, 25030 Jean Minjoz, France. franck.bonnetain@univ-fcomte.fr.
Thomas SeufferleinDepartment of Internal Medicine, University Hospital Ulm, 89081 Ulm, Germany. Thomas.Seufferlein@uniklinik-ulm.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is one of the most commonly diagnosed cancers worldwide and nearly half of patients will develop metastatic disease at some point during the course of their disease. The goal of anticancer therapy in this context is to extend survival, while trying to maximise the patient's health-related quality of life. To this end, we need to understand how to incorporate patient-reported outcomes into clinical trials and routine practice to accurately assess if treatment strategies are providing clinical benefit for the patient. This review reflects the proceedings of a 2016 European Society of Digestive Oncology workshop, where the authors discussed the use of patient-reported outcomes to measure health-related quality of life when evaluating treatment during the management of colorectal cancer. A summary of the challenges associated with implementing patient-reported outcomes in clinical trials is provided, as well as a review of the current clinical evidence surrounding patient-reported outcomes in metastatic colorectal cancer.

Indexed as

endpointshealth-related quality of lifemetastatic colorectal cancerpatient-reported outcomesregistries

Identifiers

PMID28587143
PMCPMC5483878

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.