Evidence map›Paper›PMID 28587059›Full record

ArticleNutrients2017

Selected Risk Nutritional Factors for Chemotherapy-Induced Polyneuropathy.

Jiri Grim, Alena Ticha, Radomir Hyspler, Martin Valis, Zdenek Zadak

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Vitamin D Insufficiency as a Risk Factor for Paclitaxel-Induced Peripheral Neuropathy in SWOG S0221.Journal of the National Comprehensive Cancer Network : JNCCN · 2023
    Trial
  3. Review
  4. Article
  5. Article
  6. Chemotherapy-Induced Peripheral Neuropathy.Handbook of experimental pharmacology · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. High prevalence of peripheral neuropathy in multiple myeloma patients and the impact of vitamin D levels, a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Predictive clinical factors of chronic peripheral neuropathy induced by oxaliplatin.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  12. Observational
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiri GrimDepartment of Oncology and Radiotherapy, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech. grimj@lfhk.cuni.cz.
Alena TichaDepartment of Research and Development, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech. alena.ticha@fnhk.cz.
Radomir HysplerDepartment of Research and Development, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech. rhyspler@lfhk.cuni.cz.
Martin ValisDepartment of Neurology, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech. martin.valis@fnhk.cz.
Zdenek ZadakDepartment of Research and Development, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech. zdenek.zadak@fnhk.cz.
University Hospital Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study seeks to identify the nutritional risk factors involved in the development of neuropathies induced by chemotherapeutic treatments. Unlike the gastrointestinal or hematological adverse effects of chemotherapy there is no protective treatment strategy for polyneuropathy. The aim of this study was to find possible deficiencies in nutritional factors, which can be used for supplementation in the future for prevention of chemotherapy-induced neuropathy development. We analyzed 70 patients undergoing paclitaxel chemotherapy and evaluated the risk factors involved in chemotherapy-induced peripheral neuropathy (CIPN). Several risk factors were considered in the development of CIPN, including deficiency of vitamin B1, B6, and D and fatty acids. The occurrence of CIPN complication in 60% cases was observed. We found significant differences in vitamin D and saturated fatty acid concentration. Vitamin D levels in the group without CIPN were estimated to be 38.2 (24.95, 47.63) nmol/L, whereas in the group with CIPN it was determined to be 25.6 (19.7, 32.55) nmol/L,

Indexed as

Nutritional StatusAdultAgedAntineoplastic AgentsFatty AcidsFemaleHumansMaleMiddle AgedPolyneuropathiesRisk FactorsVitamin DAntineoplastic AgentsFatty AcidsVitamin Dchemotherapyfatty acidspolyneuropathyvitamin B1vitamin B6vitamin D

Identifiers

PMID28587059
PMCPMC5490514
OpenAlexW2619695300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.