ArticleInternational journal of epidemiology2017
Maternal consumption of artificially sweetened beverages during pregnancy, and offspring growth through 7 years of age: a prospective cohort study.
Article in International journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association between low-calorie sweetener consumption during pregnancy and child health: A systematic review and meta-analysis.Maternal & child nutrition · 2025Pooled it
- Consumption of Non-Nutritive Sweetener during Pregnancy and Weight Gain in Offspring: Evidence from Human Studies.Nutrients · 2022Pooled it
- Maternal Consumption of Ultra-Processed Foods-Rich Diet and Perinatal Outcomes: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Effects of prenatal artificial sweeteners consumption on birth outcomes: a systematic review and meta-analysis.Public health nutrition · 2021Pooled it
- Preconception Lifestyle and Cardiovascular Health in the Offspring of Overweight and Obese Women.Nutrients · 2019Trial
- High sucralose exposure in early pregnancy increases the susceptibility of heart defects in mice offspring.iScience · 2026Article
- Consumer Perceptions of Artificial Sweeteners in Food Products, Consumption Frequency, and Body Mass Index: A Multivariate Analysis.Nutrients · 2025Article
- Prenatal Diet and Infant Growth From Birth to Age 24 Months.JAMA network open · 2024Article
- Artificial Sweetener and the Risk of Adverse Pregnancy Outcomes: A Mendelian Randomization Study.Nutrients · 2024Article
- Artificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank.Cardiovascular diabetology · 2024Article
- Article
- Precision stratification of prognostic risk factors associated with outcomes in gestational diabetes mellitus: a systematic review.Communications medicine · 2024Article
- Unveiling the profound influence of sucralose on metabolism and its role in shaping obesity trends.Frontiers in nutrition · 2024Review
- Aspartic Acid in Health and Disease.Nutrients · 2023Review
- Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study.Nutrients · 2023Article
- Associations between sugar-sweetened beverages before and during pregnancy and offspring overweight/obesity in Japanese women: the TMM BirThree Cohort Study.Public health nutrition · 2023Article
- Article
- Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway.JCI insight · 2023Article
- Effects of Nonnutritive Sweeteners on Body Composition Changes during Pubertal Growth.Nutrients · 2023Article
- Transplacental Transport of Artificial Sweeteners.Nutrients · 2023Article
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13 authors.
Funding
Abstract
Background: Artificial sweeteners are widely replacing caloric sweeteners. Data on long-term impact of artificially sweetened beverage (ASB) consumption during pregnancy on offspring obesity risk are lacking. We prospectively investigated intake of ASBs and sugar-sweetened beverages (SSBs) during pregnancy in relation to offspring growth through age 7 years among high-risk children born to women with gestational diabetes. Methods: In a prospective study of 918 mother-singleton child dyads from the Danish National Birth Cohort, maternal dietary intake was assessed by a food frequency questionnaire during pregnancy. Offspring body mass index z-scores (BMIZ) and overweight/obesity status were derived using weight and length/height at birth, 5 and 12 months and 7 years. Linear regression and Poisson regression with robust standard errors were used, adjusting for major risk factors. Results: Approximately half of women reported consuming ASBs during pregnancy and 9% consumed daily. Compared to never consumption, daily ASB intake during pregnancy was positively associated with offspring large-for-gestational age [adjusted relative risk (aRR) 1.57; 95% CI: 1.05, 2.35 at birth], BMIZ (adjusted β 0.59; 95% CI: 0.23, 0.96) and overweight/obesity (aRR 1.93; 95% CI; 1.24, 3.01) at 7 years. Per-serving-per-day substitution of ASBs with water during pregnancy was related to a lower overweight/obesity risk at 7 years (aRR 0.83; 95% CI: 0.76, 0.91), whereas SSB substitution with ASBs was not related to a lower risk (aRR 1.14; 95% CI: 1.00, 1.31). Conclusions: Our findings illustrated positive associations between intrauterine exposure to ASBs and birth size and risk of overweight/obesity at 7 years. Data with longer follow-up are warranted.
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