Evidence map›Paper›PMID 28586464›Full record

ArticleInternational journal of epidemiology2017

Does unmeasured confounding influence associations between the retail food environment and body mass index over time? The Coronary Artery Risk Development in Young Adults (CARDIA) study.

Pasquale E Rummo, David K Guilkey, Shu Wen Ng, Katie A Meyer, Barry M Popkin, Jared P Reis, James M Shikany, Penny Gordon-Larsen

Abstract read
In one paragraph

Article in International journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Food Swamps Predict Obesity Rates Better Than Food Deserts in the United States.International journal of environmental research and public health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pasquale E RummoDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC, USA.
David K GuilkeyCarolina Population Center, Chapel Hill, North Carolina.
Shu Wen NgDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC, USA.
Katie A MeyerDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC, USA.
Barry M PopkinDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC, USA.
Jared P ReisDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD, USA.
James M ShikanyDivision of Preventive Medicine, University of Alabama at Birmingham, AL, USA.
Penny Gordon-LarsenDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, NC, USA.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Stuart J Frank · 2013 to 2026
$19.5M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Obesity and Metabolic Risk Disparities: Underlying Food Environment FactorsR01HL104580 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2010 to 2014
$2.2M
Environmental Changes and Health Outcomes across 25 Years: Four US CitiesR01HL114091 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2011 to 2014
$2.1M
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS R01 HL104580NHLBI NIH HHS R01 HL114091NICHD NIH HHS P2C HD050924NIDDK NIH HHS P30 DK056350NIDDK NIH HHS P30 DK079626NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Background: Findings in the observational retail food environment and obesity literature are inconsistent, potentially due to a lack of adjustment for residual confounding. Methods: Using data from the CARDIA study (n = 12 174 person-observations; 6 examinations; 1985-2011) across four US cities (Birmingham, AL; Chicago, IL; Minneapolis, MN; Oakland, CA), we used instrumental-variables (IV) regression to obtain causal estimates of the longitudinal associations between the percentage of neighbourhood food stores or restaurants (per total food outlets within 1 km network distance of respondent residence) with body mass index (BMI), adjusting for individual-level socio-demographics, health behaviours, city, year, total food outlets and market-level prices. To determine the presence and extent of bias, we compared the magnitude and direction of results with ordinary least squares (OLS) and random effects (RE) regression, which do not control for residual confounding, and with fixed effects (FE) regression, which does not control for time-varying residual confounding. Results: Relative to neighbourhood supermarkets (which tend to be larger and have healthier options than grocery stores), a higher percentage of grocery stores [mean = 53.4%; standard deviation (SD) = 31.8%] was positively associated with BMI [β = 0.05; 95% confidence interval (CI) = 0.01, 0.10] using IV regression. However, associations were negligible or null using OLS (β = -0.001; 95% CI = -0.01, 0.01), RE (β = -0.003; 95% CI = -0.01, 0.0001) and FE (β = -0.003; 95% CI = -0.01, 0.0002) regression. Neighbourhood convenience stores and fast-food restaurants were not associated with BMI in any model. Conclusions: Longitudinal associations between neighbourhood food outlets and BMI were greater in magnitude using a causal model, suggesting that weak findings in the literature may be due to residual confounding.

Indexed as

Body Mass IndexCommerceResidence CharacteristicsRestaurantsAdolescentAdultFemaleFood AnalysisFood SupplyHumansMaleMultivariate AnalysisObesityProspective StudiesRegression AnalysisRisk FactorsendogeneityInstrumental-variables regressionneighbourhoodsobesityretail food environmentweight

Identifiers

PMID28586464
PMCPMC5837451

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.