Evidence map›Paper›PMID 28586222›Full record

ArticleJournal of chemical information and modeling2017

Structural Characterization of Histatin 5-Spermidine Conjugates: A Combined Experimental and Theoretical Study.

Stephanie Jephthah, João Henriques, Carolina Cragnell, Sumant Puri, Mira Edgerton, Marie Skepö

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Stephanie JephthahDivision of Theoretical Chemistry, Lund University , Post Office Box 124, S-221 00 Lund, Sweden.ORCID 0000-0003-4287-506X
João HenriquesDivision of Theoretical Chemistry, Lund University , Post Office Box 124, S-221 00 Lund, Sweden.
Carolina CragnellDivision of Theoretical Chemistry, Lund University , Post Office Box 124, S-221 00 Lund, Sweden.ORCID 0000-0001-6751-0644
Sumant PuriPediatrics and Community Oral Health Sciences, Temple University , Philadelphia, Pennsylvania 19147, United States.ORCID 0000-0002-5509-007X
Mira EdgertonDepartment of Oral Biology, University at Buffalo , Buffalo, New York 14214-3092, United States.ORCID 0000-0002-9680-5908
Marie SkepöDivision of Theoretical Chemistry, Lund University , Post Office Box 124, S-221 00 Lund, Sweden.ORCID 0000-0002-8639-9993
Lund University · SETemple University · USUniversity at Buffalo, State University of New York · US

Funding

Supplements to Support Candida DNA Microarray FacilitiesR01DE010641 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EDGERTON, MIRA · 2000 to 2019
$6.7M
Advanced Training in Oral BiologyT32DE023526 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Stefan Hans-Klaus Ruhl · 2013 to 2026
$3.7M
Regulation of Candida albicans Pathogenesis by the Signaling Mucin Msb2R01DE022720 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CULLEN, PAUL JAMES, EDGERTON, MIRA · 2013 to 2017
$1.9M
NIDCR NIH HHS R01 DE010641NIDCR NIH HHS R01 DE022720NIDCR NIH HHS T32 DE023526
6 · The paper itself

Abstract

Histatin 5 (Hst5) is a naturally occurring antimicrobial peptide that acts as the first line of defense against oral candidiasis. It has been shown that conjugation of the active Hst5 fragment, Hst5

Indexed as

Molecular Dynamics SimulationHistatinsMolecular ConformationScattering, Small AngleSpermidineX-Ray DiffractionHistatinsSpermidine

Identifiers

PMID28586222
PMCPMC5592739
OpenAlexW2624467115

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.