ArticleScandinavian journal of primary health care2017
Clinical indications for antibiotic use in Danish general practice: results from a nationwide electronic prescription database.
Article in Scandinavian journal of primary health care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Clinical indications for antibiotic prescribing in Danish general practice.Scandinavian journal of primary health care · 2026Article
- Inappropriate antibiotic utilization in hospitalized patients in Ethiopia: A systematic review and meta-analysis.Exploratory research in clinical and social pharmacy · 2026Review
- The evidence landscape for direct-from-urine antibiotic susceptibility testing (AST) for urinary tract infection (UTI): a scoping review.JAC-antimicrobial resistance · 2026Review
- Role of diagnostic testing in reducing unnecessary antibiotic use for upper respiratory tract infections in Chinese primary healthcare: a mixed-methods study.BMC primary care · 2026Article
- The Danish Infection Cohort: a resource for population based infectious disease epidemiology.European journal of epidemiology · 2026Article
- Bacteriophage-mediated reduction of uropathogenicInfection and immunity · 2026Article
- Bacteriophage-mediated reduction of uropathogenicbioRxiv : the preprint server for biology · 2025Article
- The effect of focused lung ultrasound on antibiotic prescribing in patients with acute lower respiratory tract infections in Danish general practice (PLUS-FLUS): a pragmatic, randomised controlled, post-market trial.EClinicalMedicine · 2025Article
- In search of pragmatic measures and models from routinely collected electronic records to inform continuous optimization of antibiotics stewardship at primary care settings: preliminary findings from Anhui, China.BMC infectious diseases · 2025Article
- Evaluating the Effect of a Molecular Point-of-Care Test on Acute Respiratory Infections in General Practice: Protocol for a Cluster Randomized Trial.JMIR research protocols · 2025Article
- Diagnostic accuracy of dipsticks for urinary tract infections in acutely hospitalised patients: a prospective population-based observational cohort study.BMJ evidence-based medicine · 2025Observational
- Article
- Validation of Administrative Data and Timing of Point Prevalence Surveys for Antibiotic Monitoring.JAMA network open · 2024Article
- Use of antibiotics for urinary tract infections up to and after care home admission in Denmark: a nationwide study.European geriatric medicine · 2024Article
- Article
- Compulsory Indications in Hospital Prescribing Software Tested with Antibacterial Prescriptions.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024Article
- Fluoroquinolone resistance in complicated urinary tract infections: association with the increased occurrence and diversity ofFrontiers in cellular and infection microbiology · 2024Article
- Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine.Nature communications · 2023Article
- Severity and Bothersomeness of Urinary Tract Infection Symptoms in Women before and after Menopause.Antibiotics (Basel, Switzerland) · 2023Article
- Increased demand of urine cultures from Danish general practice: a five-year register-based study.Scandinavian journal of primary health care · 2023Article
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4 authors.
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Abstract
objectiveTo assess the availability and applicability of clinical indications from electronic prescriptions on antibiotic use in Danish general practice.
designRetrospective cohort register-based study including the Danish National Prescription Register.
settingPopulation-based study of routine electronic antibiotic prescriptions from Danish general practice. SUBJECTS: All 975,626 patients who redeemed an antibiotic prescription at outpatient pharmacies during the 1-year study period (July 2012 to June 2013).
main outcome measuresNumber of prescriptions per clinical indication. Number of antibiotic prescriptions per 1000 inhabitants by age and gender. Logistic regression analysis estimated the association between patient and provider factors and missing clinical indications on antibiotic prescriptions.
resultsA total of 2.381.083 systemic antibiotic prescriptions were issued by Danish general practitioners in the study period. We identified three main clinical entities: urinary tract infections (n = 506.634), respiratory tract infections (n = 456.354) and unspecified infections (n = 416.354). Women were more exposed to antibiotics than men. Antibiotic use was high in children under 5 years and even higher in elderly people. In 32% of the issued prescriptions, the clinical indication was missing. This was mainly associated with antibiotic types. We found that a prescription for a urinary tract agent without a specific clinical indication was uncommon.
conclusionClinical indications from electronic prescriptions are accessible and available to provide an overview of drug use, in casu antibiotic prescriptions, in Danish general practice. These clinical indications may be further explored in detail to assess rational drug use and congruence with guidelines, but validation and optimisation of the system is preferable.
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