Evidence map›Paper›PMID 28585879›Full record

ReviewDiabetes technology & therapeutics2017

Continuous Glucose Monitoring: A Review of Recent Studies Demonstrating Improved Glycemic Outcomes.

David Rodbard

4 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in Diabetes technology & therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 204 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 3 pooled it
30.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03842683 completednot on this map

Are Todays Continuous Glucose Monitoring Precise and Can They be Used to Reveal and Reduce Glycaemic Variability?

TypeobservationalSponsorPeter VestergaardRan2016 to 2017Enrolled472ConditionsDiabetes Type 1ArmsCGM
NCT04614623 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Defining the Role of Management Factors in Outcome Disparity in Pediatric T1D

TypeinterventionalSponsorChildren's Hospital New Orleans, LARan2020 to 2022Enrolled120ConditionsType1diabetesArmsAHCL pump, Video conferencing Application
NCT05574023 nacompletednot on this mapstarted 2021, after this paper: background citation

Impact of Continuous Glucose Monitoring (CGM) With Predictive Alarm for Hypoglycemia (Guardian Connect System) on Glycemic Control and Hypoglycemia Management in a Group of Adolescents With Type 1 Diabetes Mellitus Treated With Multiple Daily Insulin Injections (MDI).

TypeinterventionalSponsorAzienda Ospedaliera Universitaria Integrata VeronaRan2021 to 2022Enrolled20ConditionsType 1 DiabetesArmsUse of Predictive Alarm for hypoglycaemia or hyperglycaemia, Use of Alarm on Threshold for hypoglycaemia or hyperglycaemia
NCT06716671 completednot on this mapstarted 2024, after this paper: background citation

Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus

TypeobservationalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2024 to 2026Enrolled87ConditionsContinuous Glucose Monitoring, Quality of Life, Type 2 Diabetes Mellitus (T2DM)
3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 3 syntheses or guidelines pooled it, 463 citations in OpenAlex.

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  10. Use of flash glucose-sensing technology in patients with type 2 diabetes treated with liraglutide combined with CSII: a pilot study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
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144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David RodbardBiomedical Informatics Consultants LLC , Potomac, Maryland.
Clinical Research Consultants (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous Glucose Monitoring (CGM) has been demonstrated to be clinically valuable, reducing risks of hypoglycemia and hyperglycemia, glycemic variability (GV), and improving patient quality of life for a wide range of patient populations and clinical indications. Use of CGM can help reduce HbA1c and mean glucose. One CGM device, with accuracy (%MARD) of approximately 10%, has recently been approved for self-adjustment of insulin dosages (nonadjuvant use) and approved for reimbursement for therapeutic use in the United States. CGM had previously been used off-label for that purpose. CGM has been demonstrated to be clinically useful in both type 1 and type 2 diabetes for patients receiving a wide variety of treatment regimens. CGM is beneficial for people using either multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII). CGM is used both in retrospective (professional, masked) and real-time (personal, unmasked) modes: both approaches can be beneficial. When CGM is used to suspend insulin infusion when hypoglycemia is detected until glucose returns to a safe level (low-glucose suspend), there are benefits beyond sensor-augmented pump (SAP), with greater reduction in the risk of hypoglycemia. Predictive low-glucose suspend provides greater benefits in this regard. Closed-loop control with insulin provides further improvement in quality of glycemic control. A hybrid closed-loop system has recently been approved by the U.S. FDA. Closed-loop control using both insulin and glucagon can reduce risk of hypoglycemia even more. CGM facilitates rigorous evaluation of new forms of therapy, characterizing pharmacodynamics, assessing frequency and severity of hypo- and hyperglycemia, and characterizing several aspects of GV.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2HumansHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulinAmbulatory glucose profile (AGP)Artificial pancreas (AP)Automated insulin delivery (AID)Closed-loop control (CLC)Continuous glucose monitoring (CGM)Continuous subcutaneous insulin infusion (CSII)Flash glucose monitoringGlycemic variability (GV)HyperglycemiaHypoglycemiaMultiple daily injections (MDI)Sensor-augmented pump (SAP)Time in range (TIR)Type 1 diabetes (T1DM)Type 2 diabetes (T2DM).

Identifiers

PMID28585879
PMCPMC5467105
OpenAlexW2624348061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.