Evidence map›Paper›PMID 28585492›Full record

ArticleTechnology in cancer research & treatment2017

Electrosensitization Increases Antitumor Effectiveness of Nanosecond Pulsed Electric Fields

Claudia Muratori, Andrei G Pakhomov, Loree Heller, Maura Casciola, Elena Gianulis, Sergey Grigoryev, Shu Xiao, O N Pakhomova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Technology in cancer research & treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia MuratoriFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Andrei G PakhomovFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Loree HellerFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Maura CasciolaFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Elena GianulisFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Sergey GrigoryevFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Shu XiaoFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
O N PakhomovaFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanosecond pulsed electric fields are emerging as a new modality for tissue and tumor ablation. We previously reported that cells exposed to pulsed electric fields develop hypersensitivity to subsequent pulsed electric field applications. This phenomenon, named electrosensitization, is evoked by splitting the pulsed electric field treatment in fractions (split-dose treatments) and causes

Indexed as

electrosensitizationirreversible electroporationnanoporationnanosecond pulsed electric fields (nsPEF)tumor ablation

Identifiers

PMID28585492
PMCPMC5762058

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.