Evidence map›Paper›PMID 28585238›Full record

ArticleMagnetic resonance in medicine2018

Three-dimensional mapping of brain venous oxygenation using R2* oximetry.

Deng Mao, Yang Li, Peiying Liu, Shin-Lei Peng, Jay J Pillai, Hanzhang Lu

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Cross-vendor harmonization of TMagnetic resonance in medicine · 2018
    Article
  9. Quantitative assessment of cerebral venous blood TMagnetic resonance in medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deng MaoThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yang LiThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Peiying LiuThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Shin-Lei PengThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jay J PillaiThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hanzhang LuThe Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2012 to 2020
$13.1M
Normalized functional MRI in human brain disordersR01MH084021 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG · 2008 to 2017
$3.6M
BOLD and its discontents: age-differences in the neurophysiology of fMRI signalR01AG047972 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG, RYPMA, BART · 2015 to 2019
$1.7M
Modulation of brain activity by control of the inspired airR01NS067015 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG · 2010 to 2013
$1.5M
Cognition and cerebrovascular function across the lifespanR01AG042753 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG · 2013 to 2015
$841k
Advanced MRI methods to image vascular physiology with respiratory manipulationsR21NS095342 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2016 to 2017
$476k
Quantification of brain metabolic rate in neonates using MRIR21NS085634 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, PEIYING · 2014 to 2015
$441k
NIA NIH HHS R01 AG042753NIA NIH HHS R01 AG047972NIBIB NIH HHS P41 EB015909NIMH NIH HHS R01 MH084021NINDS NIH HHS R01 NS067015NINDS NIH HHS R21 NS085634NINDS NIH HHS R21 NS095342
6 · The paper itself

Abstract

purposeCerebral venous oxygenation (Y

methodsThis technique separates blood signal from tissue by velocity-encoding phase contrast and measures the R2* of pure blood by multi-gradient-echo acquisition. The blood R2* was converted to Y

resultsIn vitro R2*-Y calibration plot revealed a strong dependence of blood R2* on oxygenation, with additional dependence on hematocrit. In vivo results demonstrated that the technique can provide a 3D venous oxygenation map that depicts both large sinuses and smaller cortical veins, with venous oxygenation ranging from 57 to 72%. Intrasession coefficient of variation of the measurement was 3.0%. The technique detected an average Y

conclusionsThis study demonstrated the feasibility of 3D brain oxygenation mapping without using contrast agent. Magn Reson Med 79:1304-1313, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Indexed as

AdultBrainBrain MappingCerebrovascular CirculationFemaleHumansMagnetic Resonance AngiographyMaleOximetryYoung Adultblood oxygenationblood R2*hyperoxiaMR oximetryphase contrastvenogram

Identifiers

PMID28585238
PMCPMC5718988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.