Evidence map›Paper›PMID 28585034›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease-state-of-the-evidence and clinical recommendations.

Viviany R Taqueti, Sharmila Dorbala, David Wolinsky, Brian Abbott, Gary V Heller, Timothy M Bateman, Jennifer H Mieres, Lawrence M Phillips, Nanette K Wenger, Leslee J Shaw

Abstract readConsensus Statement
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020
    Guideline
  2. Review
  3. Article
  4. Guideline for Chronic Coronary Syndrome - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  5. Article
  6. Article
  7. Quality metrics for single-photon emission computed tomography myocardial perfusion imaging: an ASNC information statement.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  8. PET/MR imaging of inflammation in atherosclerosis.Nature biomedical engineering · 2023
    Review
  9. Article
  10. Prognostic utility ofFrontiers in cardiovascular medicine · 2023
    Article
  11. Imaging of heart disease in women: review and case presentation.European journal of nuclear medicine and molecular imaging · 2022
    Review
  12. Multimodality Imaging in the Detection of Ischemic Heart Disease in Women.Journal of cardiovascular development and disease · 2022
    Review
  13. Article
  14. Review
  15. Abnormal vasodilator stress electrocardiogram with normal myocardial perfusion: Clinical decision-making and review of literature.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Review
  16. Review
  17. Review
  18. Prognostic value of myocardial perfusion imaging with D-SPECT camera in patients with ischemia and no obstructive coronary artery disease (INOCA).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Viviany R TaquetiNoninvasive Cardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, ASBI-L1 037-G, 75 Francis Street, Boston, MA, 02115, USA. vtaqueti@bwh.harvard.edu.
Sharmila DorbalaNoninvasive Cardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, ASBI-L1 037-G, 75 Francis Street, Boston, MA, 02115, USA.
David WolinskyDepartment of Cardiovascular Medicine, Cleveland Clinic Florida, Weston, FL, USA.
Brian AbbottWarren Alpert Medical School, Brown University, Providence, RI, USA.
Gary V HellerGagnon Cardiovascular Center, Morristown Medical Center, Morristown, NJ, USA.
Timothy M BatemanSaint Luke's Health System, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Jennifer H MieresHofstra Northwell School of Medicine, New York, NY, USA.
Lawrence M PhillipsLeon H. Charney Division of Cardiology, New York University Langone Medical Center, New York University School of Medicine, New York, NY, USA.
Nanette K WengerDivision of Cardiology, Department of Medicine, Emory University Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA, USA.
Leslee J ShawDivision of Cardiology, Department of Medicine, Emory University Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA, USA.

Funding

Hormones/Genes in Women's Health: From Bench to BedsideK12HD051959 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLDSTEIN, JILL M, REXRODE, KATHRYN M · 2005 to 2023
$8.8M
Extension to Coronary Flow Reserve to Assess Hidden Risk: Focus on Women, Heart Failure, and InflammationK23HL135438 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TAQUETI, VIVIANY R · 2017 to 2021
$1.1M
NHLBI NIH HHS K23 HL135438NICHD NIH HHS K12 HD051959
6 · The paper itself

Abstract

This document from the American Society of Nuclear Cardiology represents an updated consensus statement on the evidence base of stress myocardial perfusion imaging (MPI), emphasizing new developments in single-photon emission tomography (SPECT) and positron emission tomography (PET) in the clinical evaluation of women presenting with symptoms of stable ischemic heart disease (SIHD). The clinical evaluation of symptomatic women is challenging due to their varying clinical presentation, clinical risk factor burden, high degree of comorbidity, and increased risk of major ischemic heart disease events. Evidence is substantial that both SPECT and PET MPI effectively risk stratify women with SIHD. The addition of coronary flow reserve (CFR) with PET improves risk detection, including for women with nonobstructive coronary artery disease and coronary microvascular dysfunction. With the advent of PET with computed tomography (CT), multiparametric imaging approaches may enable integration of MPI and CFR with CT visualization of anatomical atherosclerotic plaque to uniquely identify at-risk women. Radiation dose-reduction strategies, including the use of ultra-low-dose protocols involving stress-only imaging, solid-state detector SPECT, and PET, should be uniformly applied whenever possible to all women undergoing MPI. Appropriate candidate selection for stress MPI and for post-MPI indications for guideline-directed medical therapy and/or invasive coronary angiography are discussed in this statement. The critical need for randomized and comparative trial data in female patients is also emphasized.

Indexed as

Coronary CirculationCost-Benefit AnalysisExercise TestFemaleFractional Flow Reserve, MyocardialHumansMaleMyocardial IschemiaMyocardial Perfusion ImagingPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonASNC consensus statementimagingStable ischemic heart diseasewomen

Identifiers

PMID28585034
PMCPMC5942593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.