Evidence map›Paper›PMID 28584821›Full record

ArticleJournal of immunology research2017

Th1/Th2 Balance and Th17/Treg-Mediated Immunity in relation to Murine Resistance to Dextran Sulfate-Induced Colitis.

Fangli Yang, Danan Wang, Yan Li, Lixuan Sang, Junfeng Zhu, Jinyan Wang, Bing Wei, Changlong Lu, Xun Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fangli YangDepartment of Immunology, China Medical University, Shenyang 110122, China.
Danan WangDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0002-1181-8831
Yan LiDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0002-7171-5164
Lixuan SangDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0002-7782-0731
Junfeng ZhuDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0001-5845-0969
Jinyan WangDepartment of Immunology, China Medical University, Shenyang 110122, China.
Bing WeiDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0001-9329-4279
Changlong LuDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0003-4982-0977
Xun SunDepartment of Immunology, China Medical University, Shenyang 110122, China.ORCID 0000-0001-5152-657X
China Medical University · CNShenyang Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of the Th17/Treg balance in the development of experimental colitis remains poorly understood.

methodsWe exploited the differential response of BALB/c mice and C57BL/6 mice towards drinking water mediated by dextran sulfate sodium (DSS) challenge.

resultsDSS-resistant BALB/c mice were characterized by low levels of IFN-

conclusionsThe intrinsic congenital capacity of mouse strains with respect to T cell proliferation determines sensitivity to experimental colitis.

Indexed as

Th1-Th2 BalanceAnimalsCell ProliferationColitis, UlcerativeColonCytokinesDextran SulfateDrinking WaterGenetic Predisposition to DiseaseInterleukin-4Interleukin-6Intestinal MucosaMiceMice, Inbred BALB CMice, Inbred C57BLReal-Time Polymerase Chain ReactionCytokinesDextran SulfateDrinking WaterInterleukin-4Interleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID28584821
PMCPMC5444015
OpenAlexW2613698834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.