ArticleJournal of International Society of Preventive & Community Dentistry
Clinicopathological Profile and Malignant Transformation in Oral Lichen Planus: A Retrospective Study.
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Understanding Oral Lichen Planus and Its Malignant Potential in the Saudi Arabian Population: A Systematic Review.Oral health & preventive dentistry · 2025Pooled it
- Use of platelet-rich plasma (PRP) and injectable platelet-rich fibrin (i-PRF) in oral lichen planus treatment: a systematic review of randomized controlled trials.BMC oral health · 2025Pooled it
- Article
- The Early Detection of Malignant Transformation of Potentially Malignant Disorders: Oral Lichen Planus.Cancers · 2025Article
- Oral Lichen Planus: Clinical Presentation, Demographic Characteristics, and Risk Factors in a Retrospective Study of 186 Polish Patients.Journal of clinical medicine · 2024Article
- Controversies regarding oral lichen planus and lichenoid-dysplastic lesions.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2024Review
- A Comparative Evaluation of Clinical Efficacy of Topical Amlexanox and Triamcinolone Acetonide in Oral Lichen Planus.Cureus · 2024Article
- A New Scoring System of Oral Lichen Planus.Journal of pharmacy & bioallied sciences · 2024Review
- Oral Potentially Malignant Disorders and Oral Cancer in Saudi Arabia: An Epidemiological Review of the Literature.Journal of clinical medicine · 2024Review
- Review
- Review
- Oral lichen planus: a microbiologist point of view.International microbiology : the official journal of the Spanish Society for Microbiology · 2021Review
- Immunohistochemical evaluation of survivin in oral lichen planus and oral squamous cell carcinoma - a retrospective study.Medicine and pharmacy reports · 2021Article
- Dysplasia in oral lichen planus: relevance, controversies and challenges. A position paper.Medicina oral, patologia oral y cirugia bucal · 2021Review
- Potential Non-Invasive Biomarkers for Early Diagnosis of Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2021Article
- Diagnostic Criteria of Oral Lichen Planus: A Narrative Review.Acta clinica Croatica · 2020Review
- Oral Mucosal Lesions - A Study of 369 Cases.Indian dermatology online journalArticle
- Evaluation of the Effectiveness of Amlexanox in the Treatment of Erosive Oral Lichen Planus: A Clinical Experience from a Tertiary Care Center.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to analyze the histopathologically diagnosed cases of oral lichen planus (OLP) in terms of age, gender, clinical variant, site, hyperpigmentation, systemic illness, grade of dysplasia, and associated malignant transformation. This study also intended to do a review of reported cases of OLP with malignant transformation. MATERIALS AND
methodsOne hundred and forty-three cases of histopathologically diagnosed OLP between 2010 and 2016 were retrospectively reviewed. Demographic and clinicopathological data including malignant transformation were obtained. The data obtained were analyzed using the Statistical Package for the Social Sciences (SPSS) software for Windows version 20.0 (IBM SPSS, SPSS Inc., Chicago, IL, USA). A review of published literature on OLP with malignant transformation was also done from 1988 to 2017 and tabulated.
resultsOLP in this study showed a male predilection with most of the patients in the third decade. The buccal mucosa (bilateral presentation) was the most common site (79.72%), and reticular type was the most common clinical type (79.02%) followed by erosive type (20.98%). The majority (92.31%) of cases were diagnosed with OLP without dysplasia. The rest (7.69%) of dysplastic cases were predominantly seen in the buccal mucosa of 58 years and above, female patients manifesting mainly as erosive type. Two patients (1.4%) previously diagnosed clinically and histopathologically as OLP developed oral squamous cell carcinoma.
conclusionThe present investigation revealed the predominance of OLP among middle-aged male population and the prevalence of bilateral involvement of buccal mucosa. Two of our cases showed malignant transformation over an average period of 3.5 years. The outcome of this study emphasizes the role of clinical follow-up of patients with OLP.
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